DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and AT1G64590

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_176640.1	Gene:	AT1G64590 / 842767	AraportID:	AT1G64590	Length:	334	Species:	Arabidopsis thaliana

Alignment Length:	314	Identity:	111/314 - (35%)
Similarity:	163/314 - (51%)	Gaps:	25/314 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 FDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQE 168
            |.|.|||..|....||...||:||||..|||.||||.||..|..::...|:..:||....||..|
plant    17 FGSRSTADHVTCNSDLRSLTAIITGATSGIGAETARVLAKRGARLVLPARSVKTAEETKARILSE 81

  Fly   169 RPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHL 233
            .|.|  ......||||||.||:|||::.:.....::.||.|||.:|..:..:.||:|.||..::|
plant    82 FPDA--EIIVMHLDLSSLTSVRRFVDDFESLNLPLNILINNAGKYAHKHALSEDGVEMTFATNYL 144

  Fly   234 SHFYLT-LQLETLFD------YKTRIIVLSSESHR-FANLPVENLAVHHLSPPPEKYWSMMAYNN 290
            .||.|| |.|:.:.:      .:.||:.::|..|. |:...::.||  .:|.....|.:..||..
plant   145 GHFLLTKLLLKKMIETAAQTGVQGRIVNVTSVVHSWFSGDMLQYLA--DISRNNRNYDATRAYAL 207

  Fly   291 AKLCNVLFAQELAQRWKQRGISVFS--LHPGNMVSSDLSRNYWFYR------LLFAIVRPFTKSL 347
            :||.|||...||::...:...:|.:  :||| :|.:.|:|:    |      |:|.:.....||:
plant   208 SKLANVLHTVELSRLLHKMDANVTANCVHPG-IVKTRLTRD----REGVVTDLVFFLTSKLLKSV 267

  Fly   348 QQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSENLIA 401
            .|||||:.|.||:..|..:.|.||::|.....||........|:||..|:.|::
plant   268 PQAAATTCYVATSPRLRNVCGKYFSDCNEARSSKSGSCNLKAQRLWTASDLLVS 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	111/314 (35%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	103/297 (35%)
AT1G64590	NP_176640.1	retinol-DH_like_SDR_c_like	36..313	CDD:212492	99/285 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3143
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.910