DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and PORA

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_200230.1	Gene:	PORA / 835507	AraportID:	AT5G54190	Length:	405	Species:	Arabidopsis thaliana

Alignment Length:	326	Identity:	94/326 - (28%)
Similarity:	156/326 - (47%)	Gaps:	53/326 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 KDLHGRTALITGANCGIGYETARSLAHHG-CEIIFACRNRSSAEAAIERIAQERPAARSRCRFAA 180
            |.|.....::|||:.|:|..||::||..| ..:|.|||:...|    ||.||.....:.......
plant    88 KTLRKGNVVVTGASSGLGLATAKALAETGKWHVIMACRDFLKA----ERAAQSAGMPKDSYTVMH 148

  Fly   181 LDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVF---ALPYTRTVDGLETTFQVSHLSHFYLT-LQ 241
            |||:||.||::||:..:::...:|.|:.||.|:   |...|.|.:|.|.:..::||.||.|: |.
plant   149 LDLASLDSVRQFVDNFRRAEMPLDVLVCNAAVYQPTANQPTFTAEGFELSVGINHLGHFLLSRLL 213

  Fly   242 LETL--FDYKT-RIIVLSSESHRFANL-----PVENL--------AVHHLSPPP----EKYWSMM 286
            ::.|  .||.: |:|::.|.:.....|     |..||        .::.|:...    ..:....
plant   214 IDDLKNSDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLAGGLNGLNSSAMIDGGDFVGAK 278

  Fly   287 AYNNAKLCNVLFAQELAQRW-KQRGISVFSLHPGNMVSSDLSRNYW-FYRLLFAIVRPFTKSL-- 347
            ||.::|:||:|..||..:|: :..||:..||:||.:.::.|.|.:. .:|.||.   ||.|.:
plant   279 AYKDSKVCNMLTMQEFHRRFHEDTGITFASLYPGCIATTGLFREHIPLFRTLFP---PFQKYITK 340

  Fly   348 ----QQAAATSIYCATANELTGLSGLY---------FNNCFFCEPSKLSKSAALQQQLWKLSENL 399
                :..|...:....|:.....||:|         |.|....|.|.:.|:    :::|::||.|
plant   341 GYVSESEAGKRLAQVVADPSLTKSGVYWSWNKTSASFENQLSQEASDVEKA----RRVWEVSEKL 401

  Fly   400 I 400
            :
plant   402 V 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	94/326 (29%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	92/322 (29%)
PORA	NP_200230.1	PLN00015	96..403	CDD:177654	92/318 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810