DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and AT5G53090

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_200121.4	Gene:	AT5G53090 / 835389	AraportID:	AT5G53090	Length:	375	Species:	Arabidopsis thaliana

Alignment Length:	322	Identity:	88/322 - (27%)
Similarity:	154/322 - (47%)	Gaps:	42/322 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAA--L 181
            |:..|.::||:..|||.||||.||..|..::.|.||..:|...|::..:|...........|  |
plant    54 LNHLTCIVTGSTSGIGRETARQLAEAGARVVMAVRNTKAAHELIQQWQKEWSGKGIPLNLEAMEL 118

  Fly   182 DLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTR--TVDGLETTFQVSHLSHFYLTLQL-- 242
            ||.||.||..|.......:|.:..||.|||:|::...:  :.||.|...||:||:...|:|.|
plant   119 DLLSLDSVVGFCNLWNARLSPLHVLINNAGIFSMGEEQKFSKDGYEQHMQVNHLAPALLSLLLLP 183

  Fly   243 ETLFDYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWK 307
            ..:....:|||.::|..|....:..:::   ::.....|:.|::.|:.:||..|:|:..|.:|..
plant   184 SLIRGSPSRIINVNSVMHYVGFVDPDDM---NVVSGKRKFTSLVGYSGSKLAQVMFSNVLLKRLP 245

  Fly   308 -QRGISVFSLHPG---NMVSSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANEL----- 363
             :..|||..|.||   ..|:.||.|   :.::.:|::..|..|.|:.:.::::.||..::
plant   246 LETRISVVCLSPGIVLTNVARDLPR---YVQVQYALIPYFIFSPQEGSRSTLFSATDAQIPEHCE 307

  Fly   364 ----------TGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSENLIA-------ELVEQEQ 408
                      |.:|    .||...:||:.:.:....:::|:.:..||.       .|:|.|:
plant   308 KLKTEDKPVCTFIS----QNCKHTKPSEEAHNVETAERVWEKTIKLIGLPLDAVERLIEGEE 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	85/314 (27%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	84/312 (27%)
AT5G53090	NP_200121.4	NADB_Rossmann	60..343	CDD:419666	80/292 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910