DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and AT5G02540

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_568102.1	Gene:	AT5G02540 / 831913	AraportID:	AT5G02540	Length:	331	Species:	Arabidopsis thaliana

Alignment Length:	311	Identity:	108/311 - (34%)
Similarity:	167/311 - (53%)	Gaps:	24/311 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 FDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQE 168
            |.|.|||.:|..|.|....||:|||...|||.||||.|:..|..::...||..:||.|...|.::
plant    16 FGSASTAEEVTQGIDATNLTAIITGGTGGIGMETARVLSKRGAHVVIGARNMGAAENAKTEILRQ 80

  Fly   169 RPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHL 233
            .  |.:|.....|||||::|::.||.|.......::.||.||||...||..:.||:|..|..:|:
plant    81 N--ANARVTLLQLDLSSIKSIKAFVREFHALHLPLNLLINNAGVMFCPYQLSEDGIELQFATNHI 143

  Fly   234 SHFYLT-LQLETLFD-YKT-----RIIVLSSESHRFA-NLPVENLAVHHLSPPPEKYWSMMAYNN 290
            .||.|| |.|:|:.: .||     ||:.:||.:|.:. ...::..:::.:.    .|....||..
plant   144 GHFLLTNLLLDTMKNTAKTSGVEGRILNVSSVAHIYTYQEGIQFDSINDIC----SYSDKRAYGQ 204

  Fly   291 AKLCNVLFAQELAQRWKQRGISVF--SLHPGNMVSSDLSRNYWFYRLLFAIVRPFT----KSLQQ 349
            :||.|:|.|.||:::.::.|:::.  |:|||.:    |:..:....||...::.|:    |::.|
plant   205 SKLANILHANELSRQLQEEGVNITANSVHPGLI----LTNLFQHTALLMRFLKFFSFYLWKNIPQ 265

  Fly   350 AAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSENLI 400
            .|||:.|.|....:.|::|.||.:|....||||::...|.|:||..|..||
plant   266 GAATTCYVALHPSVKGVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLI 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	108/311 (35%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	100/294 (34%)
AT5G02540	NP_568102.1	PRK06196	14..315	CDD:235736	106/308 (34%)
AT5G02540	NP_568102.1	retinol-DH_like_SDR_c_like	48..309	CDD:212492	87/270 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.810