DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and PORB

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001031731.1	Gene:	PORB / 828853	AraportID:	AT4G27440	Length:	401	Species:	Arabidopsis thaliana

Alignment Length:	361	Identity:	100/361 - (27%)
Similarity:	176/361 - (48%)	Gaps:	59/361 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 LAFAVEEPTQNVA-QVRQRFDSCSTALQVLHG-KDLHGRTALITGANCGIGYETARSLAHHG-CE 147
            |.|..|:..:|:| :.:....|..|..:.:.| |.|.....::|||:.|:|..||::||..| ..
plant    51 LRFKREQSLRNLAIRAQTAATSSPTVTKSVDGKKTLRKGNVVVTGASSGLGLATAKALAETGKWN 115

  Fly   148 IIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGV 212
            :|.|||:...||.|.:.:...:.:    .....|||:||.||::||:..:::.:.:|.|:.||.|
plant   116 VIMACRDFLKAERAAKSVGMPKDS----YTVMHLDLASLDSVRQFVDNFRRTETPLDVLVCNAAV 176

  Fly   213 F---ALPYTRTVDGLETTFQVSHLSHFYLT-LQLETL--FDYKT-RIIVLSSESHRFANL----- 265
            :   |...|.:.:|.|.:...:||.||.|. |.|:.|  .||.: |:|::.|.:.....|
plant   177 YFPTAKEPTYSAEGFELSVATNHLGHFLLARLLLDDLKKSDYPSKRLIIVGSITGNTNTLAGNVP 241

  Fly   266 PVENL--------AVHHLSPPPEKYWSMM----------AYNNAKLCNVLFAQELAQRW-KQRGI 311
            |..||        .::.|:.      |.|          ||.::|:||:|..||..:|: ::.|:
plant   242 PKANLGDLRGLAGGLNGLNS------SAMIDGGDFDGAKAYKDSKVCNMLTMQEFHRRFHEETGV 300

  Fly   312 SVFSLHPGNMVSSDLSRNYW-FYRLLFAIVRPFTKSL------QQAAATSIYCATANELTGLSGL 369
            :..||:||.:.|:.|.|.:. .:|.||.   ||.|.:      :..:...:....::.....||:
plant   301 TFASLYPGCIASTGLFREHIPLFRALFP---PFQKYITKGYVSETESGKRLAQVVSDPSLTKSGV 362

  Fly   370 Y--FNNCFFCEPSKLSKSAA---LQQQLWKLSENLI 400
            |  :||......::||:.|:   ..:::|::||.|:
plant   363 YWSWNNASASFENQLSEEASDVEKARKVWEISEKLV 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736	100/361 (28%)
		PRK06196	104..402	CDD:235736	95/342 (28%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	90/324 (28%)
PORB	NP_001031731.1	PLN00015	92..399	CDD:177654	90/320 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810