DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and AT4G24050

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_194136.1	Gene:	AT4G24050 / 828505	AraportID:	AT4G24050	Length:	332	Species:	Arabidopsis thaliana

Alignment Length:	311	Identity:	114/311 - (36%)
Similarity:	167/311 - (53%)	Gaps:	17/311 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 FDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQE 168
            |.|.|||.:|....||...||:||||..|||.||||.||..|..:||..||..:||.|.|||..|
plant    17 FGSKSTAEEVTENCDLRSITAVITGATSGIGAETARVLAKRGARLIFPARNVKAAEEAKERIVSE 81

  Fly   169 RPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHL 233
            .|  .:......|||||:.||:.||.:.:.....::.||.|||..|..:..:.||:|.||..::|
plant    82 FP--ETEIVVMKLDLSSIASVRNFVADFESLDLPLNLLINNAGKLAHEHAISEDGIEMTFATNYL 144

  Fly   234 SHFYLT-------LQLETLFDYKTRIIVLSSESHR-FANLPVENLAVHHLSPPPEKYWSMMAYNN 290
            .||.||       :|.......:.||:.::|..|. |:...:|.|.:  :|.|..::.:..||..
plant   145 GHFLLTNLLLNKMIQTAEETGVQGRIVNVTSGIHGWFSGDLIEYLRL--ISQPKCQFDATRAYAL 207

  Fly   291 AKLCNVLFAQELAQRWKQRG--ISVFSLHPGNMVSSDLSRNY--WFYRLLFAIVRPFTKSLQQAA 351
            :||.|||..:||:.|.::.|  ::|..:||| :|.:.|:|:.  ....|:|.:.....|::.|||
plant   208 SKLANVLHTKELSSRLQKIGANVTVNCVHPG-VVRTRLTRDREGLLTDLVFFLASKLVKTVPQAA 271

  Fly   352 ATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSENLIAE 402
            ||:.|.||...|..:||.||.:|....||.|..:::...:||..||.|:.:
plant   272 ATTCYVATNPRLVNVSGKYFTDCNETTPSGLGTNSSEATKLWAASEILVTQ 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	114/309 (37%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	106/292 (36%)
AT4G24050	NP_194136.1	PRK06197	36..319	CDD:235737	105/287 (37%)
AT4G24050	NP_194136.1	retinol-DH_like_SDR_c_like	36..313	CDD:212492	101/281 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.910