DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and AT2G37540

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_181290.1	Gene:	AT2G37540 / 818330	AraportID:	AT2G37540	Length:	321	Species:	Arabidopsis thaliana

Alignment Length:	307	Identity:	110/307 - (35%)
Similarity:	165/307 - (53%)	Gaps:	16/307 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 FDSCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQE 168
            |.|.|||..|....|....||:|||...|||.|.||.||..|..:|.|.||..:|..:.|.|.|.
plant    16 FGSASTAEDVTQAIDASHLTAIITGGTSGIGLEAARVLAMRGAHVIIAARNPKAANESKEMILQM 80

  Fly   169 RPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHL 233
            .|.|  |..:..:|:||::||:.||::.......::.||.||||...|:..|.||:|:.|..:|:
plant    81 NPNA--RVDYLQIDVSSIKSVRSFVDQFLALNVPLNILINNAGVMFCPFKLTEDGIESQFATNHI 143

  Fly   234 SHFYLT-LQLETL------FDYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNA 291
            .||.|| |.|:.:      ...:.||:.|||.:|.:..  .|.:....:: .|..|....||..:
plant   144 GHFLLTNLLLDKMKSTARESGVQGRIVNLSSIAHTYTY--SEGIKFQGIN-DPAGYSERRAYGQS 205

  Fly   292 KLCNVLFAQELAQRWKQRG--ISVFSLHPGNMVSSDLSRNYWFYRLLF-AIVRPFTKSLQQAAAT 353
            ||.|:|.:..|::|.::.|  |::.|:||| :|:::|.|...|...:| |:...|.|::.|.|||
plant   206 KLSNLLHSNALSRRLQEEGVNITINSVHPG-LVTTNLFRYSGFSMKVFRAMTFLFWKNIPQGAAT 269

  Fly   354 SIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSENLI 400
            :.|.|...:|.|::|.||.:|....|||.:.:.:|..:||..|..||
plant   270 TCYVALHPDLEGVTGKYFGDCNIVAPSKFATNNSLADKLWDFSVFLI 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	110/307 (36%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	103/290 (36%)
AT2G37540	NP_181290.1	retinol-DH_like_SDR_c_like	35..309	CDD:212492	98/279 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000061
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100091
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X72
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.810