DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and 1700003E16Rik

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_082224.1	Gene:	1700003E16Rik / 71837	MGIID:	1919087	Length:	598	Species:	Mus musculus

Alignment Length:	138	Identity:	29/138 - (21%)
Similarity:	49/138 - (35%)	Gaps:	63/138 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SEDELPPGWEERATDDGTVCYVNQQGKTSQWTHPRTGRSKRITGELPL--------GWEKYYDEQ 65
            :||   |.|.|  .::...|      .|..|..          |.:|:        ..|::::|:
Mouse   112 AED---PTWGE--DEEPLAC------TTDSWAQ----------GSVPVLHTPAPVCVEEQFHNEE 155

  Fly    66 -GKRFMFL-----NKETQQRT-----NVDPRL---------AFAVEEPTQNVAQVRQRFDSCSTA 110
             |....||     :||:|:.|     :.:|::         ||...||              ..|
Mouse   156 PGNPDQFLLGSSWDKESQKPTQPSEPSAEPKVTPRPTATLEAFEEAEP--------------GDA 206

  Fly   111 LQVLHGKD 118
            |:|.||::
Mouse   207 LEVPHGQE 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736	6/29 (21%)
		WW	54..86	CDD:197736	11/50 (22%)
		PRK06196	104..402	CDD:235736	5/15 (33%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669
1700003E16Rik	NP_082224.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		DUF4639	6..571	CDD:292118	29/138 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..190		9/38 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	222..241
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	366..396
		LamG	<436..>463	CDD:304605
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	551..571
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900