Protein Alignment Wwox and zgc:112332

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001018519.1
• Gene: zgc:112332 / 553712
• ZFINID: ZDB-GENE-050522-387
• Length: 298
• Species: Danio rerio
• Alignment Length: 285
• Identity: 107/285 - (37%)
• Similarity: 161/285 - (56%)
• Gaps: 20/285 - (7%)

  Fly   119 LHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDL 183
            |..:|.:|||||.|||.||||.||..|..::.|||:...||||...:...  :.........|||
Zfish    18 LDEKTVIITGANTGIGKETARDLARRGARVVMACRDLEKAEAARRELMDN--SGNQNIVVKKLDL 80

  Fly   184 SSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETLFDY 248
            :..:|::.|.|.|.:....::.||.|||:...||::|.||.|..|.|:||.||.|...|..|...
Zfish    81 ADTKSIKAFAELINKEEKQVNILINNAGIMMCPYSKTADGFEMQFGVNHLGHFLLIYLLLDLLKK 145

  Fly   249 KT--RIIVLSSESHRFANLPVENLAVHHLSPPPEKYWS-MMAYNNAKLCNVLFAQELAQRWKQRG 310
            .|  ||:.::|.:|.::.:.:|::       ..||.:| ..||..:||.|:|..:.||:|.:..|
Zfish   146 STPSRIVNVASVAHTWSGIHLEDI-------NSEKVYSPRRAYGQSKLANILCTRSLAKRLQGSG 203

  Fly   311 ISVFSLHPGNMVSSDLSRNYWF-YRLLFAIVRPFTKSLQQAAATSIYCATANELTGLSGLYFNNC 374
            ::|:||||| :|.|:|.||... .::.|.:..||||:..|.|.|:||||...||...||.|:::
Zfish   204 VNVYSLHPG-VVQSELFRNLSKPAQIAFKVFSPFTKTTSQGAQTTIYCAIEPELDRESGGYYSD- 266

  Fly   375 FFCEPSKLSKSAA---LQQQLWKLS 396
              |.|::.|:.|:   :.|:||:||
Zfish   267 --CGPAQCSREASDDEMAQKLWELS 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	106/283 (37%)
zgc:112332	NP_001018519.1	Rossmann-fold NAD(P)(+)-binding proteins	21..289	CDD:473865	104/280 (37%)