DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wwox and C2orf81

DIOPT Version :9

Sequence 1:NP_001285735.1 Gene:Wwox / 34090 FlyBaseID:FBgn0031972 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_001303693.1 Gene:C2orf81 / 388963 HGNCID:34350 Length:615 Species:Homo sapiens


Alignment Length:221 Identity:45/221 - (20%)
Similarity:68/221 - (30%) Gaps:89/221 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   134 GYETARSLAHHGCEIIFACRNRSSAEAAIERIAQER--------------PAARSRCRFAALDLS 184
            |:...|..|||         :|...:||::|:...|              |.:::|      .|.
Human   354 GHSDVRLSAHH---------HRMRRKAAVKRLDPARLPCHWVRPLAEVLVPDSQTR------PLE 403

  Fly   185 SLRSVQRFVEEIK-----------QSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYL 238
            :.|..|| .|:.|           ..||...:..|..|:   |:.....|....|...:|.    
Human   404 AYRGRQR-GEKTKARAEPQALGPGTRVSPAAFFPLRPGI---PFRDLDSGPALLFPTLNLG---- 460

  Fly   239 TLQLETLFDYKTRIIVLSSESHRFANLPVENLAVHHLSPPP----------EKYWSMMAY----- 288
                            |||.|.. :.||:.|..:..|:..|          .|.|..:.:     
Human   461 ----------------LSSPSLE-SKLPLPNSRIRFLTTHPVLPDVARSRSPKLWPSVRWPSGWE 508

  Fly   289 NNAKLCNVLFA---------QELAQR 305
            ..|:|...|:|         .|||.|
Human   509 GKAELLGELWAGRTRVPPQGLELADR 534

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WwoxNP_001285735.1 WW 13..43 CDD:197736
WW 54..86 CDD:197736
PRK06196 104..402 CDD:235736 45/221 (20%)
human_WWOX_like_SDR_c-like 121..402 CDD:187669 45/221 (20%)
C2orf81NP_001303693.1 DUF4639 9..614 CDD:292118 45/221 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1208
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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