Protein Alignment Wwox and CG11200

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_611471.1
• Gene: CG11200 / 37301
• FlyBaseID: FBgn0034500
• Length: 355
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 79/298 - (26%)
• Similarity: 136/298 - (45%)
• Gaps: 39/298 - (13%)

  Fly   122 RTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSL 186
            |.|:|||.|.|||......|......::...|:...||.|:..|. :..|.:.:.....||:..|
  Fly    68 RIAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETAVASIV-DLNATKGKLICEQLDVGDL 131

  Fly   187 RSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLT------LQLETL 245
            :||:.|.:.||:..|.:|.|:.|||:...|:..|.||.|:.|.::.|.||.||      |:....
  Fly   132 KSVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLLPQLRAAGK 196

  Fly   246 FDYKTRIIVLSSESHRFANLPVENL-AVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRW--K 307
            ....:||:.:||..:....:..::: ...|       |:...||:.:||..:||.:.|....  :
  Fly   197 EGRNSRIVNVSSCVNLIGRINYKDINGTKH-------YYPGTAYSQSKLAQILFTRHLQTLLDAE 254

  Fly   308 QRGISVFSLHPGNMVSSDLSRNY------WFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGL 366
            :..:.|..:||| :|.:||..:.      .|.:|.|       |:.::.:.|.::.|....:.|.
  Fly   255 KSHVQVNVVHPG-IVDTDLFEHSATTSVPIFKKLFF-------KTPERGSRTVVFAAIDPSIEGQ 311

  Fly   367 SGLYFNN----CFFCEPSKLSKSAALQQQLWKLSENLI 400
            .|.|.:|    .|..:..|.:|.    :||::.|.:|:
  Fly   312 GGTYLSNGGKGPFHPDAKKPAKC----EQLFQFSCDLL 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	79/298 (27%)
CG11200	NP_611471.1	Rossmann-fold NAD(P)(+)-binding proteins	67..338	CDD:473865	76/289 (26%)