Protein Alignment Wwox and Ldsdh1

DIOPT Version :9

• Sequence 1: NP_001285735.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_572436.1
• Gene: Ldsdh1 / 31726
• FlyBaseID: FBgn0029994
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 55/263 - (20%)
• Similarity: 104/263 - (39%)
• Gaps: 62/263 - (23%)

  Fly   118 DLHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFA-AL 181
            |::|:..||||...|:|.|.|...|..|..|:....|..:....::.|......|     |. ..
  Fly    55 DVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKNNGGKA-----FGYVC 114

  Fly   182 DLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALP----YTRTVDGLETTFQVSHLSHFYLTLQL 242
            :::....:....:::::....|..::.|||:  :|    ...|.:.:...::::.||||::....
  Fly   115 NVTKREELIELAQKVRKEHGFIHVVVNNAGI--MPCHPLLEHTENEIRLMYEINVLSHFWIIQAF 177

  Fly   243 ETLFDYKTR----IIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFA---- 299
              |.|...|    |:.|||.:..|..:                       |....|...||
  Fly   178 --LPDMIERNEGSIVALSSCAGLFGLI-----------------------NLVPYCGTKFAVRGY 217

  Fly   300 -----QELAQRWKQRGISVFSLHPGNMVSSDLSRN--YWF---YRLLFA------IVRPFTKSLQ 348
                 :||.|:..|..:.:.:::| .|:.:.|.:|  |.|   ::|:.|      |:....:.|:
  Fly   218 MAALVEELRQKNPQNNVKLTTIYP-YMIDTGLCKNPRYRFPNLFKLIPADVAAGSIIEAQRQGLE 281

  Fly   349 QAA 351
            :||
  Fly   282 EAA 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	55/263 (21%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	54/260 (21%)
Ldsdh1	NP_572436.1	adh_short	59..248	CDD:278532	43/221 (19%)
		NADB_Rossmann	60..287	CDD:304358	53/258 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447650
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930