DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wwox and CG3603

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001259199.1	Gene:	CG3603 / 31289	FlyBaseID:	FBgn0029648	Length:	249	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	58/217 - (26%)
Similarity:	91/217 - (41%)	Gaps:	49/217 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 LHGRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDL 183
            |.|:.||:|||..|||..|.|.||..|.::|...||..:|:..::.:..||.||      ..:|:
  Fly     6 LAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAA------LEVDV 64

  Fly   184 SSLRSVQRFVEEIKQSVSHIDYLILN-AGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETLFD 247
            ||.:|||..|.|..:.......:::| ||:       |.||             ||....|..:|
  Fly    65 SSAQSVQFSVAEALKKFQQAPTIVVNSAGI-------TRDG-------------YLLKMPERDYD 109

  Fly   248 ------YKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMA-YNNAKLCN--------VL 297
                  .|...:|..:.:.......:||..:.:||       |::| .||....|        :.
  Fly   110 DVYGVNLKGTFLVTQAYAKAMIEQKLENGTIVNLS-------SIVAKMNNVGQANYAATKAGVIS 167

  Fly   298 FAQELAQRWKQRGISVFSLHPG 319
            |.:..::.:.:.||.|..:.||
  Fly   168 FTEVASKEFGKFGIRVNCILPG 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	58/217 (27%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	57/215 (27%)
CG3603	NP_001259199.1	fabG	6..248	CDD:235546	58/217 (27%)
CG3603	NP_001259199.1	BKR_SDR_c	9..248	CDD:187594	56/214 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447715
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930