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Protein Alignment Wwox and Cbr1

DIOPT Version :9

Sequence 1:	NP_001285735.1	Gene:	Wwox / 34090	FlyBaseID:	FBgn0031972	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_062043.1	Gene:	Cbr1 / 29224	RGDID:	2286	Length:	277	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	60/280 - (21%)
Similarity:	115/280 - (41%)	Gaps:	77/280 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 ALITGANCGIGYETARSLAHHGC-----EIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDL 183
            ||:||||.|||:...|.|    |     :::...|:.|....|::::..|..:.    ||..||:
  Rat     8 ALVTGANKGIGFAIVRDL----CRKFLGDVVLTARDESRGHEAVKQLQTEGLSP----RFHQLDI 64

  Fly   184 SSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTF----QVSHLSHFYLT----L 240
            .:.:|::...:.:.|....::.|:.|||:    ..:.||  .|.|    :|:..::|:.|    .
  Rat    65 DNPQSIRALRDFLLQEYGGLNVLVNNAGI----AFKVVD--PTPFHIQAEVTMKTNFFGTQDVCK 123

  Fly   241 QLETLFDYKTRIIVLSS---------------ESHRFANLPVENL-------------AVHHLSP 277
            :|..:...:.|::.:||               :..|...:..|.|             .||
  Rat   124 ELLPIIKPQGRVVNVSSSVSLRALKSCSPELQQKFRSETITEEELVGLMNKFIEDAKKGVH---- 184

  Fly   278 PPEKYWSMMAYNNAKL----CNVLFAQELAQRWKQRGISVFSLHPGNMVSSDLSRNYWFYRLLFA 338
             .::.|...||...|:    .:.::|::|.:..::..|.:.:..|| .|.:|::.
  Rat   185 -AKEGWPNSAYGVTKIGVTVLSRIYARKLNEERREDKILLNACCPG-WVRTDMAG---------- 237

  Fly   339 IVRPFTKSLQQAAATSIYCA 358
              ...|||.::.|.|.:|.|
  Rat   238 --PKATKSPEEGAETPVYLA 255

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.