Protein Alignment Wwox and Dhrsx

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001028498.2
• Gene: Dhrsx / 236082
• MGIID: 2181510
• Length: 335
• Species: Mus musculus
• Alignment Length: 290
• Identity: 91/290 - (31%)
• Similarity: 130/290 - (44%)
• Gaps: 33/290 - (11%)

  Fly   121 GRTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSS 185
            ||.|::|||..|||..|||.||..|..::.|..:....:..:..|..|  ....|..|..|||:|
Mouse    43 GRVAIVTGATAGIGRSTARQLARLGMCVVVAGNDEHCGQEVVSSIRAE--MGSDRAHFLPLDLAS 105

  Fly   186 LRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQLETLFDYK- 249
            |.||:.|..:.:.....:..|:.||||...|...|.||.|....|:.|.||.|||.|.......
Mouse   106 LASVRGFARDFRALGLPLHLLVNNAGVMLEPRAETEDGFERHLGVNFLGHFLLTLLLLPALRASG 170

  Fly   250 -----TRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRWKQR 309
                 :|::.:.|.:|....:.:.:|...|...|      ..||..:||...|||.:|.:....|
Mouse   171 AEGRGSRVVTVGSATHYVGTVDMADLHGRHAYSP------YAAYAQSKLALALFALQLQRILDAR 229

  Fly   310 GISVFS--LHPGNMVSSDLSRNY-WFYR--------LLFAIVRPFTKSLQQAAATSIYCATANEL 363
            |..|.|  ..|| :|.::|.|:. |..|        |:|       ||.::.|.|.:|.|.|.||
Mouse   230 GDPVTSNMADPG-VVDTELYRHAGWVLRTVKRFLGWLVF-------KSPEEGAWTLVYAAAAPEL 286

  Fly   364 TGLSGLYFNNCFFCEPSKLSKSAALQQQLW 393
            .|:.|.|..:....||...::...||::||
Mouse   287 EGVGGRYLRDEAEAEPLGTARDQELQRRLW 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	91/290 (31%)
Dhrsx	NP_001028498.2	retinol-DH_like_SDR_c_like	43..316	CDD:212492	89/288 (31%)