Protein Alignment Wwox and dhs-17

DIOPT Version :10

• Sequence 1: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001041109.1
• Gene: dhs-17 / 178990
• WormBaseID: WBGene00000980
• Length: 286
• Species: Caenorhabditis elegans
• Alignment Length: 307
• Identity: 84/307 - (27%)
• Similarity: 131/307 - (42%)
• Gaps: 56/307 - (18%)

  Fly   122 RTALITGANCGIGYETARSLAHHGCE-IIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSS 185
            ||.|||||..|||.:||..||.|... :|...|......|..:.|.:|.... |...:.|.|.:.
 Worm     8 RTILITGATDGIGKQTALDLAAHPDNFVIIHGRTEEKCIATKDWIGKENGNC-SNIDYVAGDFAV 71

  Fly   186 LRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYL-TLQLETLFDYK 249
            |:.|....||:::....::.|:.||||.......|.||:|:||||::|:|:.| .|.|..|...:
 Worm    72 LKEVAIIAEEVERRFPELNVLLCNAGVLYPRRLETKDGMESTFQVNYLAHYLLCNLLLPVLSHNR 136

  Fly   250 TRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRW----KQRG 310
            :.:||:.|..|.:.:|...::..      .::|...:.|:.:||...|.|..|.:|.    :...
 Worm   137 SNVIVVGSVLHTWPSLDWADVMA------TKEYEKYLQYSRSKLMCHLMAFALHRRMNIARQHVN 195

  Fly   311 ISVFSL----HPGNMVSSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGL----- 366
            :::..|    .|.|  :..|..               |.:|..:.:|...|..|..|..|
 Worm   196 VNIIELGKEKEPNN--NGKLRT---------------TSALSSSMSTLSICRQAGNLAQLIEGPC 243

  Fly   367 ----SGLYFNNCFFCEPS-KLSKSAA------LQQQLWKLSENLIAE 402
                ||.|.      :|| |..:|.:      ||::||..|:.|..|
 Worm   244 LEKISGKYL------DPSGKQMRSGSDATDERLQERLWAYSKELCHE 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	83/305 (27%)
dhs-17	NP_001041109.1	retinol-DH_like_SDR_c_like	7..275	CDD:212492	79/296 (27%)