Protein Alignment Wwox and Hsd17b7

DIOPT Version :9

• Sequence 1: NP_001285735.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: XP_011237060.1
• Gene: Hsd17b7 / 15490
• MGIID: 1330808
• Length: 377
• Species: Mus musculus
• Alignment Length: 341
• Identity: 93/341 - (27%)
• Similarity: 134/341 - (39%)
• Gaps: 101/341 - (29%)

  Fly   122 RTALITGANCGIGYE-TARSLAH----HGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAAL 181
            :..|||||:.|||.. ..|.||.    |.|   .||||.|.|.|..:.:....|:|  ......:
Mouse     3 KVVLITGASSGIGLALCGRLLAEDDDLHLC---LACRNLSKARAVRDTLLASHPSA--EVSIVQM 62

  Fly   182 DLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALP-----------YTR---------------- 219
            |:|||:||.|..||:||....:|||.||||:...|           ::|
Mouse    63 DVSSLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFTTAEGILTQN 127

  Fly   220 ---TVDGLETTFQVSHLSHFYLTLQLETLF---DYKTRIIVLSSESHRFANLPVENLAVHHLSPP 278
               |.|||:..|:.:...||.|..:||.|.   |..:::|..||.:.:.||..:|::. |...|.
Mouse   128 DSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKANFSLEDIQ-HSKGPE 191

  Fly   279 PEKYWSMMAYNNAKLCNVLFAQELAQRWKQRGISVFSLHPG----NMVSSDLSRNYW------FY 333
            |        |:::|....|....|.:.:.|:|:....:.||    ||....|....|      .:
Mouse   192 P--------YSSSKYATDLLNVALNRNFNQKGLYSSVMCPGVVMTNMTYGILPPFIWTLLLPIMW 248

  Fly   334 RLLFAI------------------------VRPFTKSLQQAAATSIYCATANELTG--------L 366
            .|.|.:                        :.|.||   .|:|||.:  ..|.:||        |
Mouse   249 LLRFFVNALTVTPYNGAEALVWLFHQKPESLNPLTK---YASATSGF--GTNYVTGQKVHNPLML 308

  Fly   367 SGLYFNN--CFFCEPS 380
            |.:.|.|  .:...||
Mouse   309 SSVMFTNPSAWLLHPS 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	93/341 (27%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	93/341 (27%)
Hsd17b7	XP_011237060.1	3KS_SDR_c	2..280	CDD:187645	77/290 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R408
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940