DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7227 and scarb2b

DIOPT Version :9

Sequence 1:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	XP_009299911.1	Gene:	scarb2b / 564077	ZFINID:	ZDB-GENE-170406-1	Length:	523	Species:	Danio rerio

Alignment Length:	519	Identity:	136/519 - (26%)
Similarity:	232/519 - (44%)	Gaps:	44/519 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLLASFSLFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNWTNSEKFSDPTV 79
            ||||..:||:....:.:....|:..:.|..|:.:.:.|::|...:.::.:.||.||.|.|.....
Zfish    18 LLLAGIALFASGLFQTLIHNKLKKEITLTEGSKVFATWKNPPPPVYMEFFFFNVTNPEAFLKGEA 82

  Fly    80 KPRFEELGPYRFTERMQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRPT-DPIVAPNLLIVGLY 143
            |.|..|:|||.:.|...|.||.:.|..:.|:......|.|.|:.|||.|: |.:...|:..|.:.
Zfish    83 KARLSEMGPYTYREYRPKHNVSFVDNGTKVAAYTPKVFVFVPEKSVGDPSVDMVTTVNIPAVAVM 147

  Fly   144 QKMVMWSPMLRSLMLLALNIYGKEQAMIRPASDWMFDGFDTPMIKMSKMVPPSLVPEMKFPYEKI 208
            .::.....::.|.|.|.:...|.|..|.....:.:: ||..|::...:    |:.||..   |..
Zfish   148 NRIKGAGFLVSSAMSLYMKSIGAEMFMTHTVDELLW-GFKDPLLTKLR----SIKPETD---EFF 204

  Fly   209 GYAYPRNGSMEIYGHHNVYTGRDEFQKLGQIARWRYNNVT---EASPRCKLKGSAGE-FHPIPLV 269
            |....:|||.:  |....:||...:...|:|..|:...:.   :.:....:.|:.|. |||. |.
Zfish   205 GLMLHKNGSDD--GEFVYHTGEHNYLDYGRIFTWKGEKLMSFWKTNQSNMINGTDGSAFHPF-LT 266

  Fly   270 KGRPISYFLPDLCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPDNSCYCQDNCQEVRSGL 334
            |...:..|..||||.:.:.:......:||.|:.:......:|:||:||:|..:|....:.:..|:
Zfish   267 KEERLDVFTADLCRSIHMRFEKEVEVKGIPAYRFTPPRAVLASGTNNPENEGFCLTPKKCLDDGV 331

  Fly   335 LNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPKTGMVLEIKARIMANLL 399
            |::|.|..|.||..|:|||...|..|.:.|||:.|..::|:..:.|.|..|:.:....|...|:.
Zfish   332 LDVSVCRQGAPVVVSFPHFHLGDEKYVQAVEGLSPVHEQHQTFLDLNPTMGVPVRAMKRAQINIH 396

  Fly   400 VEPKTHL-IYRTARRTFFPLIWADYNVRITD-------DLLVYVKLMP----ILEFVGKICGILG 452
            :|..|.. :.|....|.||:|:.:.:|.|.:       .||:.|.|:.    ||..:|.|..|:.
Zfish   397 LERVTGFPMTRNLESTIFPIIFLNESVVIDNASAERIQKLLLVVTLVSHFPLILVALGVILLIVA 461

  Fly   453 VVLGLLMVFWYPHQMIWQKSLMHKIEISSIETNSSLE---PVKNNDVEDSPLLKGLQYAAAKDG 513
            |:|.   |.:|          .:|.|:...:...:..   |....|...:|:...:.....|:|
Zfish   462 VILA---VRYY----------QNKTEVKRFDFAEAFHCTAPSAKKDTSYAPVSAKVDDQDEKNG 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	128/464 (28%)
scarb2b	XP_009299911.1	CD36	30..463	CDD:279474	119/443 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030