DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7227 and RGD1565355

DIOPT Version :9

Sequence 1:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001102688.1	Gene:	RGD1565355 / 499985	RGDID:	1565355	Length:	472	Species:	Rattus norvegicus

Alignment Length:	487	Identity:	123/487 - (25%)
Similarity:	218/487 - (44%)	Gaps:	70/487 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SVLGLLLASFS-----LFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNWTN 70
            :::|.:||.|.     :..:|..:.|:|     .:||..||:....|......:....:||:..|
  Rat    13 AIIGAVLAVFGGILMPVGDLLIEKTIKR-----EVVLEEGTIAFKNWVKTGTTVYRQFWIFDVQN 72

  Fly    71 SEKFSDPTVKPRFEELGPYRFTER-MQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRPTDPIVA 134
            .|:.:..:.|.:.::.|||.:..| :.|.|:....::||||:.:.:...|:|.||||...|....
  Rat    73 PEEVAKNSSKIKVKQRGPYTYRVRYLAKENITQDPKDSTVSFVQPNGAIFEPSLSVGTENDNFTV 137

  Fly   135 PNLLIVG---LYQKMVMWSPMLRSLMLLALNIYGKEQAMIRPASDWMFD---------GFDTPMI 187
            |||.:..   :||...               |.|....:|:.:...||.         |:..|.:
  Rat   138 PNLAVAAAPHIYQNSF---------------IQGVLNNLIKKSKSSMFQTRSLKELLWGYKDPFL 187

  Fly   188 KMSKMVPPSLVPEMKFPYE-KIGYAYPRNGSMEIYGHHNVYTGRDEFQKLGQIARWR-YNNVTEA 250
                    ||:|   :|.. .:|..||.|.:::  |.:.|:.|:|...|:..|..:: ..|::..
  Rat   188 --------SLIP---YPISTTVGVFYPYNNTVD--GVYKVFNGKDNINKVAIIDTYKGKRNLSYW 239

  Fly   251 SPRC-KLKGS-AGEFHPIPLVKGRPISYFLPDLCRELQVDYSGTTIFEGIDAFVYRGSARNMANG 313
            ...| .:.|: |..|.|. :.|.|.:.:|.||:||.:...:......:||..:.:.......|:.
  Rat   240 KSYCDMINGTDAASFPPF-VEKSRTLRFFSPDICRSIYAVFESEVNLKGIPVYRFVLPVNAFASP 303

  Fly   314 TDNPDNSCYC-----QDNCQEVRSGLLNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDR 373
            ..||||.|:|     .:||...  |:|:|..|..|.||:.|.|||..|.|...|.::|:.|::|.
  Rat   304 LQNPDNHCFCTEKVISNNCTSY--GVLDIGKCKEGKPVYISLPHFLHASPDVSEPIQGLNPNEDE 366

  Fly   374 HEMVIMLEPKTGMVLEIKARIMANLLVEP--KTHLIYRTARRTFFPLIWADYNVRITDDLLVYVK 436
            |...:.:||.||..|:...|:..|:||:|  |...:....|....|::|.:....|.|:.:...:
  Rat   367 HRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALRNLKRPYIVPILWLNETGTIGDEKVEIFR 431

  Fly   437 -----LMPILEFVGKICGILGVVLGLLMVFWY 463
                 .:.:|:.|.::..::||::.:..:..|
  Rat   432 NQVTGKINLLDLVERVLLVVGVLMFVAFMISY 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	122/483 (25%)
RGD1565355	NP_001102688.1	CD36	16..461	CDD:279474	122/480 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820