DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7227 and dsb

DIOPT Version :9

Sequence 1:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001097477.1	Gene:	dsb / 38252	FlyBaseID:	FBgn0035290	Length:	615	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	146/508 - (28%)
Similarity:	238/508 - (46%)	Gaps:	65/508 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TSVLGLLLASFSLFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNWTNSEKF 74
            |.:||::|:|........::.:..|         ..|:....||.|.:.....|||:|.||.:.|
  Fly    89 TLILGIILSSMPWLDYFILKNLRLW---------NDTLSYHYWQRPGVIRLTKLYIYNVTNPDGF 144

  Fly    75 SDPTVKPRFEELGPYRFTERMQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRPTDPIVAPNLLI 139
            .... ||..:|:||:.:.|.||||||::|:.|.||||:.:....|.|:||:.:.| ||..||:.:
  Fly   145 LRGE-KPHLQEVGPFVYREDMQKVNVKFHENNYTVSYQHKKILQFVPELSIDKDT-PITTPNIPL 207

  Fly   140 VGLYQKMVMWSPMLRSLMLLALNIY---GKEQAMIRPASDWMFDGFDTPMIKMSKMVPPSLVPEM 201
            :.|    ...||.|..|:...:::.   .:.:..|...::.:..|:|..::.::.    ...|:.
  Fly   208 LTL----TSLSPKLGYLLSKTISVVVTAAQFKPFINVTAEQLAFGYDDALVSLAH----RFYPKH 264

  Fly   202 KFPYEKIGYAYPRNGSM-EIYGHHNVYTGRDEFQKLGQI---------ARWRYNNVTEASPRC-K 255
            ..|.|::|....|||:: |:   .:|.||.|...:.|.|         ..|       :.|.| .
  Fly   265 MRPMERMGLLLGRNGTLTEV---SSVKTGMDSMDQFGYIDQLNGLDHLPHW-------SEPPCTS 319

  Fly   256 LKGSAGEFHPIP--LVKGRPISYFLPDLCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPD 318
            :.||.|.|.| |  |.|...:..:..||||.:.:.|..:...:||.|.::|....:..:...||:
  Fly   320 IAGSEGSFFP-PRELTKSEVVHIYDKDLCRIIPLKYVESLEKDGIAADLFRLPNNSYGDSAHNPE 383

  Fly   319 NSCYCQDNCQEVRSGLLNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPK 383
            |.||.....:.:: ||.|||.|.||.||:.|.||||::.|.....|||:||::::||....::||
  Fly   384 NKCYDTSEYEPIQ-GLQNISPCQYGAPVYISNPHFFESHPDLLNSVEGLKPEREKHETYFKIQPK 447

  Fly   384 TGMVLEIKARIMANLLVEPKTHLIY--RTARRTFFPLIWADYNVRITDDLLVYVK--------LM 438
            .|:.||.|.||..||.| .:...:|  |..|...||::|.:..:   .:|...:|        :.
  Fly   448 LGVPLEGKVRIQLNLKV-TRAKDVYPVRDFRDFVFPVMWLEEGI---SELTPAIKRWIYLGTVIA 508

  Fly   439 PILEFVGKICGILGVVLGLLMVF--WYPHQMIWQKSLMHKIEIS--SIETNSS 487
            |....:|....|||....::..|  .|.:.|..|...:..:|:.  |:...||
  Fly   509 PSAVPIGSYLMILGGAFAIIFSFVRAYQNFMFAQDPTLEILEMGRRSLRRGSS 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	138/477 (29%)
dsb	NP_001097477.1	CD36	103..532	CDD:279474	133/463 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450713
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4750
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	7	6.850