DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7227 and scarb2c

DIOPT Version :9

Sequence 1:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001352071.1	Gene:	scarb2c / 337532	ZFINID:	ZDB-GENE-030131-5789	Length:	478	Species:	Danio rerio

Alignment Length:	474	Identity:	124/474 - (26%)
Similarity:	210/474 - (44%)	Gaps:	66/474 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLLASFSLFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNWTN-SEKFSDPT 78
            ||:...:|.....::::....::..:||..||...|:||:|...:.:..|.||.|| :|..|..
Zfish    18 LLICGIALELTRVLQKLVNNTVKQQIVLENGTEAFSVWQNPPPPVYMQFYFFNLTNPAEVMSGD- 81

  Fly    79 VKPRFEELGPYRFTERMQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRPTDPIVAPNLLIVGLY 143
             ||...::|||.:.|......|::.|..:.|:......:.|:|.:|.|...|.:...|:..|.:.
Zfish    82 -KPSVVQIGPYTYREYRPMEEVKFMDNGTRVAAINPKTYVFEPNMSRGSQDDLVRTVNIPAVTVM 145

  Fly   144 QKMVMWSPMLRSLMLLALNIYGKEQAMIRPASDWM-------FD---------GFDTPMIKMSKM 192
            :|.                   |:..:.|..||.|       |:         |::.|::|...|
Zfish   146 EKY-------------------KDSILARLISDLMKAKGVGVFETFRVGDLLWGYEDPLLKELHM 191

  Fly   193 VPPSLVPEMKFPYEKIGYAYPRNGSMEIYGHHNVYTGRDEFQKLGQIARWRYNNVTE--ASPRCK 255
                |||:..|     |..|.:||:.  |..:.:.||:.::|....|..|.......  :|..|.
Zfish   192 ----LVPDDHF-----GLFYKKNGTE--YDSYVLLTGKPDYQDFASIDEWNGQRSLNWWSSEECN 245

  Fly   256 -LKGSAG-EFHPIPLVKGRPISYFLPDLCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPD 318
             :.|:.| .|||| :.|...:..|..||||.|.|.|......:|:..|.:...|...::...|||
Zfish   246 MINGTDGASFHPI-ITKADRLYIFSSDLCRSLYVQYECDVSVQGVPGFRFVPPADVFSSPDINPD 309

  Fly   319 NSCYCQDNCQEVRSGLLNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPK 383
            |:.:|......:.|||||.|.|..|.|:..|.|||::||..:.:.:.||||.|:.|:....:.|.
Zfish   310 NAGFCVPPGHCLGSGLLNASVCKQGAPIIMSSPHFYQADQKFVDDIWGMKPIKEEHQTFADINPL 374

  Fly   384 TGMVLEIKARIMANLLVEPKTHLIYRTARRTF-FPLIWADYNVRITDDLL-----------VYVK 436
            ||:||:...|:..|:.::..:........:|. ||:::.:.:..|.::..           |.:.
Zfish   375 TGIVLQGAKRVQVNVYLQQHSSFSQTGKIQTLVFPVMYINESAFIDEESAKKLHAVVLNANVVIN 439

  Fly   437 LMPILEFVGKICGILGVVL 455
            :..|:..||.:.||:.:||
Zfish   440 IPFIVISVGILLGIIFIVL 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	124/474 (26%)
scarb2c	NP_001352071.1	CD36	15..457	CDD:307331	122/471 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920