DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7227 and crq

DIOPT Version :9

Sequence 1:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_001245823.1	Gene:	crq / 33219	FlyBaseID:	FBgn0015924	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	130/472 - (27%)
Similarity:	234/472 - (49%)	Gaps:	29/472 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KQRIWQTSVLGLLLASFSLFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNW 68
            ::::|... ||.:.....:..|::...|...::|..:.|:|||.....|....:.|.:..|:|||
  Fly    10 QRKVWVFG-LGSVFLLLGILIVVFWPGIADNLVEDGLTLKPGTDAYESWLEAPIPIYLSFYMFNW 73

  Fly    69 TNSEKFSDPTVKPRFEELGPYRFTERMQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRPTDPIV 133
            ||.|...:|.:||.|.|:|||.|.|:.:|.|..::| |:||:|..|..:.|||:.|.|...|.:.
  Fly    74 TNPEDIRNPDIKPNFVEMGPYTFLEKHKKENYTFYD-NATVAYYERRTWFFDPERSNGTLDDMVT 137

  Fly   134 APNLLIVGLYQKMVMWSPMLRSLMLLALNIYGKEQAMIRPASDWMFDGFDTPMIKMSKMVPPSLV 198
            |.:.:...:..:|.....:::.::...||..|.:..:.:|..:|:|:|:...:.....:...:
  Fly   138 AAHAITATVADEMRDQRKIVKKIINFMLNHEGGKLYVTKPVGEWIFEGYQDNITDFLNLFNTT-- 200

  Fly   199 PEMKFPYEKIGYAYPRNGSMEIYGHHNVYTGRDEFQKLGQIARWRYNNVTEAS----PRCKLKGS 259
             ::..||::.|:...||.|:...|...::||.|:...||::..|  |..:|..    |...:.|:
  Fly   201 -KIDIPYKRFGWLADRNESLTYDGLFTIHTGTDDISNLGRLTHW--NGKSETGFYEMPCGIVNGT 262

  Fly   260 AGEFHPIPLVKGRPISYFLPDLCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPDNSCYCQ 324
            .|:..|..:.....|:.|..|.||.:.:...||....|:.|..:.|:...:.:|.:.|:.:|:|.
  Fly   263 TGDMFPPKMNVNDEITIFATDACRFMNLRPRGTYENHGLTATKWVGTEETLDSGENYPNQACFCD 327

  Fly   325 ----DNCQEVRSGLLNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPKTG 385
                |.|.  ::|::...:|....|:::|:|||:.||..|.:.|.||||:|::||..:.:||.||
  Fly   328 EARFDECP--KTGVVECKACRDKAPIYSSFPHFYLADQSYVDAVSGMKPEKEKHEFFLAVEPITG 390

  Fly   386 MVLEIKARIMANLLVEPKTHL-IYRTARRTFFPLIWADYNVRITDDLLVYVKLMPILEFVGKICG 449
            :.:::..||..|:::||.... |||..::...|:.|.|....::.:|....||...|...|.|.|
  Fly   391 VPVQVHGRIQINMMIEPDDDFDIYRGVQKVLMPMFWFDQYAELSSELASKAKLAINLSSYGIIFG 455

  Fly   450 -----------ILGVVL 455
                       |.|:.|
  Fly   456 YSMIAFASVFLITGITL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	129/463 (28%)
crq	NP_001245823.1	CD36	19..470	CDD:307331	126/458 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450685
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0007610
OrthoInspector	1	1.000	-	-		mtm4750
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	8	7.850