DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7227 and scarb2a

DIOPT Version :9

Sequence 1:	NP_001245934.1	Gene:	CG7227 / 34088	FlyBaseID:	FBgn0031970	Length:	518	Species:	Drosophila melanogaster
Sequence 2:	NP_775366.1	Gene:	scarb2a / 192340	ZFINID:	ZDB-GENE-020419-29	Length:	531	Species:	Danio rerio

Alignment Length:	516	Identity:	121/516 - (23%)
Similarity:	234/516 - (45%)	Gaps:	55/516 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VLGLLLASFSLFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNWTNSEKFSD 76
            :||:.|....:|..:..|:|::     .:.|...:.:...|.:|...:.:..:.||.||.::|..
Zfish    20 ILGIALLLAQVFQTMIQERIKK-----EITLAENSRVLDGWINPPPPVYMQYFFFNVTNPDEFLA 79

  Fly    77 PTVKPRFEELGPYRFTERMQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRP-TDPIVAPNLLIV 140
            ...|.:..::|||.:.|...:.||.:.:..:.:.......|.|...:|.|.| .|.:...|:.::
Zfish    80 GKEKAKVTQMGPYTYREYRPRENVTYLENGTKIFATNPKSFVFLRNMSAGDPEVDRVTTVNIPMI 144

  Fly   141 GLYQKMVMWSPMLRSLMLLALNIYGKEQAMIRPASDWMFDGFDTPMIKMSKMVPPSLVPEMKFPY 205
            .:..::..:|..:|:.:.:.:...|....|.|...:.:: ||..|:  ::|:  .::.||:.
Zfish   145 AVMNELNSYSFFVRTAVSMYMGSMGMGLFMNRTVHEILW-GFKDPL--LTKL--HAMRPEVD--- 201

  Fly   206 EKIGYAYPRNGSMEIYGHHNVYTGRDEFQKLGQIARWRYNNVTE-----ASPRCKLKGSAGE-FH 264
            |..|..|.:||:.|  |....:||...:...|:|..|  |.:::     ::....:.|:.|. ||
Zfish   202 EHFGLMYNKNGTHE--GEFVFHTGEKNYMNYGKIDTW--NGISQMNWWSSNQSNMINGTDGSVFH 262

  Fly   265 PIPLVKGRPISYFLPDLCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPDNSCYCQDNCQE 329
            .. |.:...:..|..||||.:.:.|......:||.||.:...:..:|...:||.|:.:|......
Zfish   263 TF-LSRKELLYIFAADLCRSIHLGYVRDMEVKGIPAFRFAPPSDVLAPPDENPANAGFCVPAGDC 326

  Fly   330 VRSGLLNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPKTGMVLEIKARI 394
            :..|:|.:|.|..|.|:..|:|||::||..|...:|||.|:::.||..:.:.|.||:.:....|.
Zfish   327 LGKGVLKVSVCRQGAPIVVSFPHFYQADERYINAIEGMNPNEEEHETYLDINPTTGVPIRACKRA 391

  Fly   395 MANLLVE-----PKTHLIYRTARRTFFPLIWADYNVRITDDLLVYVKLMPILEFVGK----ICGI 450
            ..|::::     |.|..:    ..|.||:::.:....|.|:....::::.::..|..    |...
Zfish   392 QLNIILKRVRGFPNTKFL----NETIFPIMYVNETATIDDESAAQMRMLLLIVTVVSNFPVIILA 452

  Fly   451 LGVVLGLLMVFWYPHQMIWQKSLMHKIEISSI---ETNSSLEPVK--------NNDVEDSP 500
            |||:|.::::|      :..::...|.|:..|   |...|....|        :|..||||
Zfish   453 LGVILLVVLIF------LVCRNRQRKNEVKRIDFTEAFHSFATTKDETAYTQVSNQAEDSP 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	110/465 (24%)
scarb2a	NP_775366.1	CD36	30..463	CDD:279474	106/454 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030