Protein Alignment CG7227 and Scarb2

DIOPT Version :9

• Sequence 1: NP_001245934.1
• Gene: CG7227 / 34088
• FlyBaseID: FBgn0031970
• Length: 518
• Species: Drosophila melanogaster
• Sequence 2: NP_031670.1
• Gene: Scarb2 / 12492
• MGIID: 1196458
• Length: 478
• Species: Mus musculus
• Alignment Length: 468
• Identity: 130/468 - (27%)
• Similarity: 219/468 - (46%)
• Gaps: 39/468 - (8%)

  Fly    10 TSVLGLLLASFSLFSVLYMEQIERWMLEWFMVLRPGTMISSLWQSPAMDINVDLYIFNWTNSEKF 74
            |..|.||:.|.:|......::.....:|..|||:.||.:.:.|:.|.:.:.:..|.||.||.|:.
Mouse    11 TLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFNSWEKPPLPVYIQFYFFNVTNPEEI 75

  Fly    75 SDPTVKPRFEELGPYRFTERMQKVNVEWHDENSTVSYRRRSRFDFDPKLSVGRPTDPIV----AP 135
            ....: |..||:|||.:.|...|.|:::.:..:|:|......:.|:...|||.|...::    .|
Mouse    76 LQGEI-PLLEEVGPYTYRELRNKANIQFGENGTTISAVTNKAYVFERNQSVGDPNVDLIRTINIP 139

  Fly   136 NLLIVGLYQKMVMWSPMLRSLMLLALNIYGKEQAMIRPASDWMFDGFDTPMIKMSKMVPPSLVPE 200
            .|.:|.|.|     ..:||.|:...|..|.::..:|....:.:: |:...::.:..:..|.:.|
Mouse   140 LLTVVDLAQ-----LTLLRELIEAMLKAYQQKLFVIHTVHELLW-GYKDEILSLVHIFKPDVSP- 197

  Fly   201 MKFPYEKIGYAYPRNGSMEIYGHHNVYTGRDEFQKLGQIARWRYNNVTE----ASPRCK-LKGSA 260
                  ..|..|.|||:.:  |.:...||.|.:....:|..|  |..|.    .:..|. :.|:.
Mouse   198 ------NFGLFYERNGTND--GEYVFLTGEDNYLNFSKIVEW--NGKTSLDWWTTDTCNMINGTD 252

  Fly   261 GE-FHPIPLVKGRPISYFLP-DLCRELQVDYSGTTIFEGIDAFVYRGSARNMANGTDNPDNSCYC 323
            |: ||  ||:....:.|..| ||||.:.:.:|.....||:.||.|:..|..:||.::|. ..|..
Mouse   253 GDSFH--PLISKDEVLYLFPSDLCRSVHITFSSFENVEGLPAFRYKVPAEILANTSENA-GFCIP 314

  Fly   324 QDNCQEVRSGLLNISSCWYGTPVFASYPHFFKADPYYGEQVEGMKPDKDRHEMVIMLEPKTGMVL 388
            :.||.:  ||:||||.|..|.|:..|:|||::||..:...::||.|:|:.||..:.:.|.||::|
Mouse   315 EGNCMD--SGVLNISICKNGAPIIMSFPHFYQADEKFVSAIKGMHPNKEEHESFVDINPLTGIIL 377

  Fly   389 EIKARIMANLLVEPKTHLIYRTARRTF-FPLIWADYNVRI----TDDLLVYVKLMPILEFVGKIC 448
            ....|...|..|......:.....||. ||:::.:.:|.|    .:.|...:....::..:..|.
Mouse   378 RGAKRFQINTYVRKLDDFVETGDIRTMVFPVMYLNESVLIDKETANQLKSVINTTLVVTNIPYII 442

  Fly   449 GILGVVLGLLMVF 461
            ..|||..||:..:
Mouse   443 MALGVFFGLVFTW 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7227	NP_001245934.1	CD36	13..463	CDD:279474	129/465 (28%)
Scarb2	NP_031670.1	CD36	28..455	CDD:279474	124/449 (28%)
		Important for interaction with GBA	155..191		5/36 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930