Protein Alignment pes and SCARB2

DIOPT Version :9

• Sequence 1: NP_001137808.1
• Gene: pes / 34087
• FlyBaseID: FBgn0031969
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_005497.1
• Gene: SCARB2 / 950
• HGNCID: 1665
• Length: 478
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 133/475 - (28%)
• Similarity: 235/475 - (49%)
• Gaps: 48/475 - (10%)

  Fly    16 LGICC-----------IASGIYL-----FRNWIDMFTRMRGQEMALSPNSRSFEGWKVSPLPLDF 64
            :|.||           :.:.:.|     |:..:|....   :::.|...:.:|:.|:..|||:..
Human     1 MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIE---KKIVLRNGTEAFDSWEKPPLPVYT 62

  Fly    65 DIYLFNWTNPDDFYVGSNKKPHFEQLGPYRFREKPDKVDIEWHNHNASVSFHKKSWFYFDAAGSN 129
            ..|.||.|||::...|  :.|..|::|||.:||..:|.:|::.::..::|......:.|:...|.
Human    63 QFYFFNVTNPEEILRG--ETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSV 125

  Fly   130 GS-LWDKVTTVNSVAHSAARRAAVDW----FARTGVNIANKLYRQGVTITKTVDEMLFKGYEHPF 189
            |. ..|.:.|:|...     ...::|    |.|..:....|.|:|.:.:|.||||:|: ||:...
Human   126 GDPKIDLIRTLNIPV-----LTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLW-GYKDEI 184

  Fly   190 ISVGKLLRPQDVPYKRIGYHYPRNGSSEFDGDINMFTGADDIAKMGQIHTWNNLTHTGAF-EGTC 253
            :|:..:.||...||  .|..|.:||::  |||....||.|......:|..||..|....: ...|
Human   185 LSLIHVFRPDISPY--FGLFYEKNGTN--DGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKC 245

  Fly   254 GQVHGSMGEFFPPNLGTKDTV-YMYMPKMCRAIPLDYVETVTVHGVTAYKFSGTRHAVDNGTLYP 317
            ..::|:.|:.|.| |.|||.| |::....||::.:.:.:..:|.|:.|:::......:.|.:
Human   246 NMINGTDGDSFHP-LITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTS--- 306

  Fly   318 DTRCYCV-GGKCMPSGVINIGPCSFNASVYMSFPHFYMADPSYLEAIEGLRPEREKHEFFMALEP 381
            |...:|: .|.|:.|||:|:..|...|.:.|||||||.||..::.||||:.|.:|.||.|:.:.|
Human   307 DNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINP 371

  Fly   382 NAGVPMDVGGGFQANYYMEPIPGITLYENVPTVMIPMMWCEERVRVSEEIAADI-ALVPLIVLLG 445
            ..|:.:.....||.|.|::.:.......::.|::.|:|:..|.|.:.:|.|:.: :::...:::.
Human   372 LTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIIT 436

  Fly   446 QIVTGILLAG---GLICTCW 462
            .|...|:..|   ||:.| |
Human   437 NIPYIIMALGVFFGLVFT-W 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pes	NP_001137808.1	CD36	14..463	CDD:279474	133/475 (28%)
SCARB2	NP_005497.1	CD36	28..455	CDD:307331	128/446 (29%)
		Important for interaction with GBA	155..191		12/36 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5605
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.880