Protein Alignment pes and SCARB1

DIOPT Version :10

• Sequence 1: NP_609168.2
• Gene: pes / 34087
• FlyBaseID: FBgn0031969
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001354910.1
• Gene: SCARB1 / 949
• HGNCID: 1664
• Length: 552
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 147/560 - (26%)
• Similarity: 246/560 - (43%)
• Gaps: 101/560 - (18%)

  Fly    11 LGIVLLGICCIASGIYLFRNWIDMFTRMRGQEMALSPNSRSFEGWKVSPLPLDFDIYLFNWTNPD 75
            ||:.  |:.|...|..:......:..:...:.:.:.|:|.||..||..|:|....:|.|:..||.
Human    14 LGVA--GLLCAVLGAVMIVMVPSLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSVYFFDVMNPS 76

  Fly    76 DFYVGSNKKPHFEQLGPYRFREKPDKVDIEWHNHNASVSFHKKSWFYFDAAGSNGSLWDKVTTVN 140
            :...|  :||...:.|||.:||...|.:|.: |:|.:|||.:...|.|..:.|:||..|.:...|
Human    77 EILKG--EKPQVRERGPYVYREFRHKSNITF-NNNDTVSFLEYRTFQFQPSKSHGSESDYIVMPN 138

  Fly   141 SVAHSAARRAAVDWFARTGVNIANKLYRQGVTIT-------------KTVDEMLFKGYEHPFISV 192
            .:...||            |.:.||.....:.:|             :||.|::: ||:.|.:::
Human   139 ILVLGAA------------VMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMW-GYKDPLVNL 190

  Fly   193 GKLLRPQDVPYK-RIGYHYPRNGSSEFDGDINMFTGADDIAKMGQIHTWNNLTHTGAFEG-TCGQ 255
            .....|...|:| :.|.....|.|.  .|...:|||..:|:::..:..||.|:....:.. .|..
Human   191 INKYFPGMFPFKDKFGLFAELNNSD--SGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNM 253

  Fly   256 VHGSMGEFFPPNLGTKDTVYMYMPKMCRAIPLDYVETVTVHGVTAYKFSGTRHAVDNGTLYPDTR 320
            ::|:.|:.:||.:..:.::..|.|:.||::.|.|.|:....|:..|:|...:....||::||...
Human   254 INGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYKESGVFEGIPTYRFVAPKTLFANGSIYPPNE 318

  Fly   321 CYCVGGKCMPSGVINIGPCSFNASVYMSFPHFYMADPSYLEAIEGLRPEREKHEFFMALEPNAGV 385
            .:|   .|:.||:.|:..|.|:|.:::|.|||..|||...||:.||.|.:|.|..|:.:.|..|:
Human   319 GFC---PCLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSLFLDIHPVTGI 380

  Fly   386 PMDVGGGFQANYYMEPIPGITLYENVPTVMIPMMWCEERVRVSEE----IAADIALVPLIVLLGQ 446
            ||:.....|.:.||:.:.||.....:..|::|::|..|...:..|    ....:.|:|.::...|
Human   381 PMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLVLMPKVMHYAQ 445

  Fly   447 IVTGILLAGG-------LIC--------------------TCW---------YPTRQVTHFCHSD 475
            .|   |||.|       :||                    .||         :||.     ..|.
Human   446 YV---LLALGCVLLLVPVICQIRSQVGAGQRAARADSHSLACWGKGASDRTLWPTA-----AWSP 502

  Fly   476 PKAKASVLRPL-----NAFGVNSS--------AATAPVAQ 502
            |  .|:|||..     :.:|:.|:        |.|.||.:
Human   503 P--PAAVLRLCRSGSGHCWGLRSTLASFACRVATTLPVLE 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pes	NP_609168.2	CD36	15..463	CDD:460076	131/502 (26%)
SCARB1	NP_001354910.1	CD36	16..446	CDD:460076	121/452 (27%)