DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pes and scarb1

DIOPT Version :9

Sequence 1:	NP_001137808.1	Gene:	pes / 34087	FlyBaseID:	FBgn0031969	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_017213428.1	Gene:	scarb1 / 387260	ZFINID:	ZDB-GENE-031126-1	Length:	511	Species:	Danio rerio

Alignment Length:	462	Identity:	124/462 - (26%)
Similarity:	224/462 - (48%)	Gaps:	34/462 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IVLLGICCIASGIYLFRNWI---DMFTRMRGQEMALSP-NSRSFEGWKVSPLPLDFDIYLFNWTN 73
            :||.|:..:...:.:|...|   |...:    .:.::| |..|:..||..|:|....:|.|:..|
Zfish    12 LVLGGMALLFGTVLVFVGPIIIDDQIVK----NVEINPKNDLSYTMWKDIPVPFFMSVYFFHIVN 72

  Fly    74 PDDFYVGSNKKPHFEQLGPYRFREKPDKVDIEWHNHNASVSFHKKSWFYFDAAGSNGSLWDKVTT 138
            ||:...|  ::|...|.|||.:||...|.:|.:| .|.:||:.:...::|:.:.|.|...|.||.
Zfish    73 PDEILKG--ERPMVIQRGPYVYRENRWKDNITFH-ENHTVSYKEYRQYFFEESMSVGDESDVVTI 134

  Fly   139 VNS-VAHSAARRAAVDWFARTGVNIANKLYRQGVTITKTVDEMLFKGYEHPFISVGKLLRPQDVP 202
            .|. |..::.....:.:..|..::...|.:.:|..:||.|.|::: ||:...:.......|..:|
Zfish   135 PNMLVLGASVMMENMPFPVRLLLSTTFKTFNEGPFLTKPVGELMW-GYDSKLVDFLNKYLPGMLP 198

  Fly   203 YK-RIGYHYPRNGSSEFDGDINMFTGADDIAKMGQIHTWNNLTHTGAFEG-TCGQVHGSMGEFFP 265
            .. :.|.....|.|:  .|...:|||.|||.|:..:.:||.|.:...:.. .|..::|:.|:.:|
Zfish   199 SSGKFGLFADFNNSN--TGLFTIFTGRDDIRKVHMVDSWNGLKNVDYWRSDQCNMINGTAGQMWP 261

  Fly   266 PNLGTKDTVYMYMPKMCRAIPLDYVETVTVHGVTAYKFSGTRHAVDNGTLYPDTRCYCVGGKCMP 330
            |.:..:.|:..|.|..||::.|.|...:...|:..|::...:....||..:|....:|   .|..
Zfish   262 PFMTKETTMPFYSPDACRSMELVYQRPLVSSGIPVYRYVSPKTLFANGADFPPNEGFC---PCRQ 323

  Fly   331 SGVINIGPCSFNASVYMSFPHFYMADPSYLEAIEGLRPEREKHEFFMALEPNAGVPMDVGGGFQA 395
            ||::|:..|...:..::|.||||.|||..|:.:.||.|..::|..|:.:.|..|||::|....|.
Zfish   324 SGLLNVSSCRHGSPTFISQPHFYNADPQLLDTVSGLSPSEDEHGLFIDIHPETGVPVNVSVRLQL 388

  Fly   396 NYYMEPIPGITLYENVPTVMIPMMWCEERVRVSEEI----AADIALVP--------LIVLLG--Q 446
            |.:::.:.||:...|:..|::||:|.||...:...:    ..::.::|        :.:.||  .
Zfish   389 NLFLKKVSGISETGNIAEVVMPMLWFEESGYIDGPVLHTFRTNLVVLPKVMEYMQYIFIALGLAA 453

  Fly   447 IVTGILL 453
            |:|.::|
Zfish   454 ILTAVIL 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pes	NP_001137808.1	CD36	14..463	CDD:279474	124/461 (27%)
scarb1	XP_017213428.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582130
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.960