DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pes and santa-maria

DIOPT Version :9

Sequence 1:	NP_001137808.1	Gene:	pes / 34087	FlyBaseID:	FBgn0031969	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_609121.2	Gene:	santa-maria / 34024	FlyBaseID:	FBgn0025697	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	236/560 - (42%)
Similarity:	348/560 - (62%)	Gaps:	30/560 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RLGIVLLGICCIASGIYLFRNWIDMFTRMRGQEMALSPNSRSFEGWKVSPLPLDFDIYLFNWTNP 74
            :|.|.:.|.|....||.....|:|:|..:..:||||:|::|.:|.||..|:.|..||||:|||||
  Fly    16 KLIIGIFGFCLGLFGILCGMFWVDLFDWIMHKEMALAPDTRVYENWKSPPIDLSLDIYLYNWTNP 80

  Fly    75 DDFYVGS-NKKPHFEQLGPYRFREKPDKVDIEWHNHNASVSFHKKSWFYFDAAGSNGSLWDKVTT 138
            :||  |: :.||..||:|||||.|:||||||.||..||||::.::|.||||||||||||.|::||
  Fly    81 EDF--GNLSTKPILEQVGPYRFIERPDKVDIHWHPENASVTYRRRSLFYFDAAGSNGSLDDEITT 143

  Fly   139 VNSVAHSAARRAAVDW--FARTGVNIANKLYRQGVTITKTVDEMLFKGYEHPFISVGKLL----R 197
            :|:||.|||..|.. |  ..|:.|::..|:|...:::.|::||:||.||....|.|...:    .
  Fly   144 LNAVALSAAATAKY-WPPVKRSLVDVGLKMYGAEMSVQKSIDELLFTGYNDAMIDVAMAMPIFGD 207

  Fly   198 PQDVPYKRIGYHYPRNGSSEFDGDINMFTGADDIAKMGQIHTWNNLTHTGAFEGTCGQVHGSMGE 262
            ...||:.:.|:.|.||||::..|..|:|||||.:||:||:|:||...:||.|:..||..:||.||
  Fly   208 EVKVPFDKFGWFYTRNGSADLTGVFNVFTGADQLAKLGQMHSWNYQENTGFFDSYCGMTNGSAGE 272

  Fly   263 FFPPNLGTKDTVYMYMPKMCRAIPLDYVETVTVHGVTAYKFSGTRHAVDNGTLYPDTRCYCVGGK 327
            |.|.:|...|:|.::.|.|||.|||||||||.:.|:..|||||...:|||||.||:..|:| ||:
  Fly   273 FQPQHLKPGDSVGLFTPDMCRTIPLDYVETVDIEGLEGYKFSGGPRSVDNGTQYPENLCFC-GGQ 336

  Fly   328 CMPSGVINIGPCSFNASVYMSFPHFYMADPSYLEAIEGLRPEREKHEFFMALEPNAGVPMDVGGG 392
            |:||||:||..|.|.:.|:||:|||:.|||.|.:.:|||.|.::.|||:|.::|:.|:|::|...
  Fly   337 CVPSGVMNISSCRFGSPVFMSYPHFFNADPYYPDQVEGLSPNQKDHEFYMVVQPSTGIPLEVAAR 401

  Fly   393 FQANYYMEPIPGITLYENVPTVMIPMMWCEERVRVSEEIAADIALVPLIVLLGQIVTGILLAGGL 457
            ||.|..:|||.||:||..:|.:..|::|.|::||::.::|..:.::|:::|.|.|..||.|..|:
  Fly   402 FQVNMLVEPIQGISLYTGIPRIFFPLVWFEQKVRITPDMADQLKVLPIVMLSGHIFAGICLIVGI 466

  Fly   458 ICTCWYPTRQVTHFCHS---DPKAKASV---LRPLNAFG----VNSSAATAPVAQLFRNNISSSG 512
            ...||.|.:.:...|.:   |.:.|...   .:..:.|.    :.|.|:|....:..:.:..||
  Fly   467 TLLCWTPVQILLASCRNRRYDLRTKTKTNGQYKSRSQFSSAEELKSKASTLVCEKSVKGSPDSS- 530

  Fly   513 NERVGVRLLDYNRDSGIRLESGTMES-SHRERLISEDSPD 551
                  .||:..|...| ::|.|.|| :.....||::..|
  Fly   531 ------PLLEKGRKPTI-IKSQTGESVATASTAISDNKQD 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pes	NP_001137808.1	CD36	14..463	CDD:279474	212/455 (47%)
santa-maria	NP_609121.2	CD36	23..474	CDD:279474	213/454 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450674
Domainoid	1	1.000	248	1.000	Domainoid score	I2091
eggNOG	1	0.900	-	-		E1_KOG3776
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	1	1.000	-	-		FOG0007610
OrthoInspector	1	1.000	-	-		mtm4750
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11923
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
	10	9.860