DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pes and scarb2c

DIOPT Version :9

Sequence 1:	NP_001137808.1	Gene:	pes / 34087	FlyBaseID:	FBgn0031969	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001352071.1	Gene:	scarb2c / 337532	ZFINID:	ZDB-GENE-030131-5789	Length:	478	Species:	Danio rerio

Alignment Length:	464	Identity:	131/464 - (28%)
Similarity:	221/464 - (47%)	Gaps:	35/464 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VLLGICCIASGIYLFRNWIDMFTRMRGQEMALSPNSRSFEGWKVSPLPLDFDIYLFNWTNPDDFY 78
            |||.||.||  :.|.|....:......|::.|...:.:|..|:..|.|:....|.||.|||.:
Zfish    16 VLLLICGIA--LELTRVLQKLVNNTVKQQIVLENGTEAFSVWQNPPPPVYMQFYFFNLTNPAE-- 76

  Fly    79 VGSNKKPHFEQLGPYRFREKPDKVDIEWHNHNASVSFHKKSWFYFDAAGSNGSLWDKVTTVNSVA 143
            |.|..||...|:|||.:||.....::::.::...|:......:.|:...|.||..|.|.|||..|
Zfish    77 VMSGDKPSVVQIGPYTYREYRPMEEVKFMDNGTRVAAINPKTYVFEPNMSRGSQDDLVRTVNIPA 141

  Fly   144 HSAARRAAVDWFARTGVNIANKLYRQGVTITKT--VDEMLFKGYEHPFISVGKLLRPQDVPYKRI 206
            .:...:......||.   |::.:..:||.:.:|  |.::|: |||.|.:....:|.|.|    ..
Zfish   142 VTVMEKYKDSILARL---ISDLMKAKGVGVFETFRVGDLLW-GYEDPLLKELHMLVPDD----HF 198

  Fly   207 GYHYPRNGSSEFDGDINMFTGADDIAKMGQIHTWN---NLTHTGAFEGTCGQVHGSMGEFFPPNL 268
            |..|.:|| :|:|..: :.||..|......|..||   :|....:.|  |..::|:.|..|.|.:
Zfish   199 GLFYKKNG-TEYDSYV-LLTGKPDYQDFASIDEWNGQRSLNWWSSEE--CNMINGTDGASFHPII 259

  Fly   269 GTKDTVYMYMPKMCRAIPLDYVETVTVHGVTAYKFSGTRHAVDNGTLYPDTRCYCV-GGKCMPSG 332
            ...|.:|::...:||::.:.|...|:|.||..::|........:..:.||...:|| .|.|:.||
Zfish   260 TKADRLYIFSSDLCRSLYVQYECDVSVQGVPGFRFVPPADVFSSPDINPDNAGFCVPPGHCLGSG 324

  Fly   333 VINIGPCSFNASVYMSFPHFYMADPSYLEAIEGLRPEREKHEFFMALEPNAGVPMDVGGGFQANY 397
            ::|...|...|.:.||.||||.||..:::.|.|::|.:|:|:.|..:.|..|:.:......|.|.
Zfish   325 LLNASVCKQGAPIIMSSPHFYQADQKFVDDIWGMKPIKEEHQTFADINPLTGIVLQGAKRVQVNV 389

  Fly   398 YMEPIPGITLYENVPTVMIPMMWCEERVRVSEEIA---------ADIAL-VPLIVLLGQIVTGIL 452
            |::.....:....:.|::.|:|:..|...:.||.|         |::.: :|.||:...|:.||:
Zfish   390 YLQQHSSFSQTGKIQTLVFPVMYINESAFIDEESAKKLHAVVLNANVVINIPFIVISVGILLGII 454

  Fly   453 LAGGLICTC 461
            .   ::..|
Zfish   455 F---IVLMC 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pes	NP_001137808.1	CD36	14..463	CDD:279474	131/464 (28%)
scarb2c	NP_001352071.1	CD36	15..457	CDD:307331	130/459 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920