Protein Alignment pes and Cd36

DIOPT Version :10

• Sequence 1: NP_609168.2
• Gene: pes / 34087
• FlyBaseID: FBgn0031969
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_031669.3
• Gene: Cd36 / 12491
• MGIID: 107899
• Length: 472
• Species: Mus musculus
• Alignment Length: 477
• Identity: 123/477 - (25%)
• Similarity: 219/477 - (45%)
• Gaps: 36/477 - (7%)

  Fly     6 RHCARL-GIVLLGICCIASGIYLFRNWIDM-FTRMRGQEMALSPNSRSFEGWKVSPLPLDFDIYL 68
            |:|..: |.|:..:..:..||.:...  || ..:...:|:.|...:.:|:.|..:...:....::
Mouse     5 RNCGLIAGAVIGAVLAVFGGILMPVG--DMLIEKTIKREVVLEEGTTAFKNWVKTGTTVYRQFWI 67

  Fly    69 FNWTNPDDFYVGSNKKPHFEQLGPYRFREK-PDKVDIEWHNHNASVSFHKKSWFYFDAAGSNGSL 132
            |:..||||....|: |...:|.|||.:|.: ..|.:|.....:.:|||.:.:...|:.:.|.|:.
Mouse    68 FDVQNPDDVAKNSS-KIKVKQRGPYTYRVRYLAKENITQDPEDHTVSFVQPNGAIFEPSLSVGTE 131

  Fly   133 WDKVTTVNSVAHSAARRAAVDWFARTGVNIANKLYRQGVTITKTVDEMLFKGYEHPFISVGKLLR 197
            .|..|.:| :|.:||.....:.|.:..:|...|..:..:..|:::.|:|: ||:.||:|:
Mouse   132 DDNFTVLN-LAVAAAPHIYQNSFVQVVLNSLIKKSKSSMFQTRSLKELLW-GYKDPFLSL----- 189

  Fly   198 PQDVPY---KRIGYHYPRNGSSEFDGDINMFTGADDIAKMGQIHTWNNLTHTGAFEGTCGQVHGS 259
               |||   ..:|..||.|.:  .||...:|.|.|:|:|:..|.::....:...:...|..::|:
Mouse   190 ---VPYPISTTVGVFYPYNDT--VDGVYKVFNGKDNISKVAIIESYKGKRNLSYWPSYCDMINGT 249

  Fly   260 MGEFFPPNLGTKDTVYMYMPKMCRAIPLDYVETVTVHGVTAYKFSGTRHAVDNGTLYPDTRCYC- 323
            ....|||.:....|:..:...:||:|...:...:.:.|:..|:|....:|..:....||..|:|
Mouse   250 DAASFPPFVEKSRTLRFFSSDICRSIYAVFGSEIDLKGIPVYRFVLPANAFASPLQNPDNHCFCT 314

  Fly   324 ---VGGKCMPSGVINIGPCSFNASVYMSFPHFYMADPSYLEAIEGLRPEREKHEFFMALEPNAGV 385
               :...|...||::||.|.....||:|.|||..|.|...|.||||.|..::|..::.:||..|.
Mouse   315 EKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLHPNEDEHRTYLDVEPITGF 379

  Fly   386 PMDVGGGFQANYYMEPIPGITLYENVP-TVMIPMMWCEERVRVSEEIAA--DIALVPLIVLLGQI 447
            .:......|.|..::|...|...:|:. ..::|::|..|...:.:|.|.  ...:...|.|||.:
Mouse   380 TLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFKTQVTGKIKLLGMV 444

  Fly   448 VTGILLAGGLI--------CTC 461
            ...:|..|.::        |.|
Mouse   445 EMALLGIGVVMFVAFMISYCAC 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pes	NP_609168.2	CD36	15..463	CDD:460076	119/467 (25%)
Cd36	NP_031669.3	CD36	14..463	CDD:460076	118/463 (25%)
		Required for interaction with thrombospondins, THBS1 and THBS2. /evidence=ECO:0000269|PubMed:15748999	93..120		6/26 (23%)
		Interaction with PTK2, PXN and LYN. /evidence=ECO:0000250|UniProtKB:P16671	460..472		2/7 (29%)