Protein Alignment pes and Scarb2

DIOPT Version :9

• Sequence 1: NP_001137808.1
• Gene: pes / 34087
• FlyBaseID: FBgn0031969
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_446453.1
• Gene: Scarb2 / 117106
• RGDID: 621882
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 437
• Identity: 126/437 - (28%)
• Similarity: 220/437 - (50%)
• Gaps: 27/437 - (6%)

  Fly    41 QEMALSPNSRSFEGWKVSPLPLDFDIYLFNWTNPDDFYVGSNKKPHFEQLGPYRFREKPDKVDIE 105
            :.|.|...::.|:.|:..|||:....|.||.|||::...|  :.|..|::|||.:||..:|.:::
  Rat    39 KNMVLQNGTKVFDSWEKPPLPVYIQFYFFNVTNPEEILQG--EIPLLEEVGPYTYRELRNKANVQ 101

  Fly   106 WHNHNASVSFHKKSWFYFDAAGSNGS-LWDKVTTVN----SVAHSAARRAAVDWFARTGVNIANK 165
            :..:..::|......:.|:...|.|. ..|.:.|:|    :|...|.:.     |.|..:....|
  Rat   102 FGENGTTISAVTNKAYIFERNQSVGDPTVDLIRTINIPLLTVVEMAQQP-----FLREIIEAMLK 161

  Fly   166 LYRQGVTITKTVDEMLFKGYEHPFISVGKLLRPQDVPYKRIGYHYPRNGSSEFDGDINMFTGADD 230
            .|:|.:.:|.||.|:|: ||:...:|:..:.||...|  ..|..|.|||::  ||:....||.|:
  Rat   162 AYQQTLFVTHTVHELLW-GYKDEVLSLVHIFRPDVSP--NFGLFYERNGTN--DGEYVFLTGEDN 221

  Fly   231 IAKMGQIHTWNNLTHTGAF-EGTCGQVHGSMGEFFPPNLGTKDTVYMYMPKMCRAIPLDYVETVT 294
            .....:|..||..|....: ..||..::|:.|:.|.|.:...:|:|::....||::.:.:.....
  Rat   222 YLNFTKIVEWNGKTSLDWWTTDTCNMINGTDGDSFHPLISKDETLYIFPSDFCRSVYITFSSFEN 286

  Fly   295 VHGVTAYKFSGTRHAVDNGTLYPDTRCYCV-GGKCMPSGVINIGPCSFNASVYMSFPHFYMADPS 358
            |.|:.|:::......:.|.:   :...:|: .|.||.:||:|:..|...|.:.|||||||.||..
  Rat   287 VEGLPAFRYKVPAEILANSS---ENAGFCIPEGNCMDAGVLNVSICKNGAPIIMSFPHFYQADEK 348

  Fly   359 YLEAIEGLRPEREKHEFFMALEPNAGVPMDVGGGFQANYYMEPIPGITLYENVPTVMIPMMWCEE 423
            ::.||:|:||.:|:||.|:.:.|..|:.:.....||.|.|::.:.......|:.|::.|:|:..|
  Rat   349 FVSAIKGMRPNKEEHESFVDINPLTGIILRGAKRFQINTYVKKLDDFVETGNIRTMVFPVMYLNE 413

  Fly   424 RVRVSEEIAADIALVPLIVLLGQIVTGILLA----GGLICTCWYPTR 466
            .|.:.:|.|:.:..|....|:...:..|::|    .|||.| |...|
  Rat   414 SVLIDKETASQLKSVINTTLIVTNIPYIIMALGVFFGLIFT-WLACR 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pes	NP_001137808.1	CD36	14..463	CDD:279474	124/432 (29%)
Scarb2	NP_446453.1	CD36	34..457	CDD:395898	125/433 (29%)
		Important for interaction with GBA. /evidence=ECO:0000250	155..191		11/36 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3776
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45589
OrthoDB	1	1.010	-	-		D1106566at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11923
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X155
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930