DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7231 and fam151a

DIOPT Version :9

Sequence 1:	NP_723327.1	Gene:	CG7231 / 34086	FlyBaseID:	FBgn0031968	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001093565.1	Gene:	fam151a / 100005645	ZFINID:	ZDB-GENE-070705-105	Length:	599	Species:	Danio rerio

Alignment Length:	330	Identity:	99/330 - (30%)
Similarity:	155/330 - (46%)	Gaps:	55/330 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLTTLLFVLVAKINGSALNASNYQYQVVVEQTAPDDSQIEYIF----LKQSDMMKVWGTNLTAIT 68
            |:..||.:.:..:  ..:..|:....|.:|....|...::::.    :::.|.:..        |
Zfish    43 LIALLLIITLTSV--FVIAKSDASVDVDMEPFPSDGDMLDFLLQTGEIEEKDGLYA--------T 97

  Fly    69 WAHAVNSQQLLDEVLTETSGIDFIEADI-VLGKLNGDGEDMPIMAHPPANVSDLTLSEFLNQIIN 132
            |.||.||:..:.:.|  .|.:..:|||: |.|....:..::|||||||...||.||.|:|:.::.
Zfish    98 WYHAANSKSEMSKAL--NSDVMILEADVNVQGHNTVNETNIPIMAHPPDIYSDNTLEEWLDAVLK 160

  Fly   133 FNRDHEDQKKGVKLDFKSIEVFEGSLDILDV-NIPNVSLPTTYPVWINADILSGPVEQNRTVP-- 194
                   .|||||||||||...|.|||:|.. |...::    .|||||||||.||     .||
Zfish   161 -------SKKGVKLDFKSISAVEPSLDLLRAKNQTGIN----RPVWINADILPGP-----NVPEF 209

  Fly   195 ---VDADRFFAGC-MRYKQAVLSIGWTTNWGADFRDGEYTQQQCDDMLETLSENNVLSTGQAITF 255
               |:|..||... :::....:|.||...:.:.|.:..||:...:.|..|:..     ..|.|||
Zfish   210 WPVVNASEFFELIQLKFPDVTISPGWKVLYLSIFPNVTYTRSMVEQMYSTIRH-----LPQKITF 269

  Fly   256 PVRAGIAANSEEQLHRLVAAVNETNESTLTIWSSAGDYVDVDKLRKLIF---SFGLDRVYLDVPE 317
            ||.|.:|.|....|..|   :::::..:||:|...    :...|..|:|   :....|:|.|:.|
Zfish   270 PVHALMAKNGWPHLSWL---LSQSSRYSLTLWQGK----ENPTLNDLLFIRDNSNPQRIYYDIYE 327

  Fly   318 ELASQ 322
            .:.||
Zfish   328 PVLSQ 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7231	NP_723327.1	DUF2181	63..319	CDD:287226	89/266 (33%)
fam151a	NP_001093565.1	DUF2181	92..330	CDD:287226	90/275 (33%)
fam151a	NP_001093565.1	DUF2181	362..589	CDD:287226
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578399
Domainoid	1	1.000	125	1.000	Domainoid score	I5421
eggNOG	1	0.900	-	-		E1_KOG3748
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1117332at2759
OrthoFinder	1	1.000	-	-		FOG0003384
OrthoInspector	1	1.000	-	-		otm25619
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21184
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.810