DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Serpina7

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_112390.1	Gene:	Serpina7 / 81806	RGDID:	619833	Length:	426	Species:	Rattus norvegicus

Alignment Length:	378	Identity:	101/378 - (26%)
Similarity:	165/378 - (43%)	Gaps:	20/378 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTAL--NLPEDK-KNV 73
            |:...|..:|||....:|...||..||:.:...::|:..|:..:|..::...|  ||.:.. |.:
  Rat    55 SINADFAFRLYRKLSVENPDLNIFFSPVSISAALAMLSFGSGSSTQTQILEVLGFNLTDTPVKEL 119

  Fly    74 ATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAI 138
            ...:..|:..|........|.:.|.:|:.:.:....::...|...:..|..:...::...|...|
  Rat   120 QQGFQHLICSLNFPNNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHEI 184

  Fly   139 NDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKV-FYVSKSYQVNVN 202
            |.:|..||...:..:|  .||..:...:::|...||..|...|....|:... |.|.||..|.|.
  Rat   185 NSYVEKQTKGKIVGLI--QDLKLNIIMILVNYIHFKAQWANPFRVSKTEESSNFSVDKSTTVQVP 247

  Fly   203 MMSQVGRFKMRTSTIDQIIELPFAYS-NLSMVIVLPKDNGSLTQAEATIESYP----QIVLTEMD 262
            ||.|:.::............|...|| |...:.||||: |.:...||.:.|..    ..:|.:..
  Rat   248 MMHQLEQYYHYVDVELNCTVLQMDYSANALALFVLPKE-GHMEWVEAAMSSKTLKKWNHLLQKGW 311

  Fly   263 VHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHKAFIEIDEEGGSAG 327
            |.:.:|||.|....:|..||:.||::|.|..|:|...:...:|.::|...|||.:.|.|||...|
  Rat   312 VELFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITKDNGLKLSYAFHKAVLHIGEEGTKEG 376

  Fly   328 SASASPIRGLSD---YATSVVTFTVNSPFVFMI--RDDDNIYFRGRVVDPLKK 375
               |||..|..|   .|.......::..|:.||  :...::.|.|:||||.|:
  Rat   377 ---ASPEAGSLDQPEVAPLHAVIRLDRTFLLMILEKRTRSVLFLGKVVDPTKE 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	95/366 (26%)
Serpina7	NP_112390.1	serpinA7_TBG	48..425	CDD:381023	100/375 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.100