Protein Alignment Spn28Da and Serpina3a

DIOPT Version :10

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001161177.1
• Gene: Serpina3a / 74069
• MGIID: 1921319
• Length: 422
• Species: Mus musculus
• Alignment Length: 387
• Identity: 97/387 - (25%)
• Similarity: 182/387 - (47%)
• Gaps: 42/387 - (10%)

  Fly    12 SVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTAL--NLPE-DKKNV 73
            |:...|...||:.....|...||:.|||.:...::::.:||..||..|:...|  ||.| .:.::
Mouse    51 SINTDFAFSLYKKLALKNPHKNIVFSPLSISAALALMSLGAKDNTLEEILEGLKFNLTETPEADI 115

  Fly    74 ATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEA---------EAIKLA 129
            ...:..||..|.:.:....::..|.||:::.:.:...:.:.....::|||         ||.||
Mouse   116 HQNFGHLLQMLIQPENQVQINAGNALFIDKHLQILTEFKEKARALYKAEAFTADFQLPREATKL- 179

  Fly   130 DRLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVS 194
                    |||:|..||...:|:::  |||..:.|..::|...|:|:|...||..:|....|.:.
Mouse   180 --------INDYVRKQTQGKIKELV--SDLHRNTSMALVNFLNFQGFWNVTFDPEDTFLGNFTLD 234

  Fly   195 KSYQVNVNMM------SQVGRFKMRTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIE-- 251
            :...|||.||      :...|.:...||   ::||.: ..|.|.:.:|| |.|.:...|.:::
Mouse   235 RKRTVNVPMMKTEELTTNYFRDEEMQST---VMELNY-IGNASFLFILP-DQGRIQHVEDSLQPQ 294

  Fly   252 ---SYPQIVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVH 313
               .:.:.:...|...:.||||.:.....|.:.|..:||:::|::.:|:|.:......|:||::|
Mouse   295 SLRKWRKSLRPRMLDELSLPKFSLSQDYNLNDILPELGIKEVFSTQADLSGITGAKNIRVSQMIH 359

  Fly   314 KAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDD--DNIYFRGRVVDPL 373
            :|.:::.|....|...:.:.....|....:.:. .|:..|:::|.|.  .:|...|:|::||
Mouse   360 QAALDVTETHTEADVITIARYNFQSAKIKAKIV-KVDREFLYLILDPMFKSISVMGKVINPL 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	serpin42Dd-like_insects	12..372	CDD:381070	95/384 (25%)
Serpina3a	NP_001161177.1	serpinA3_A1AC	39..419	CDD:381019	95/384 (25%)