Protein Alignment Spn28Da and SERPING1

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_000053.2
• Gene: SERPING1 / 710
• HGNCID: 1228
• Length: 500
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 100/400 - (25%)
• Similarity: 183/400 - (45%)
• Gaps: 76/400 - (19%)

  Fly    10 TTSVLG----QFTKQLYRSFLQDNK-QYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPED 69
            |.:|||    .|:.:||.:|....| :.|:..||..:...::.:|:||..||...|.:.|:.|:|
Human   138 TEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKD 202

  Fly    70 -------KKNVATIYDKLLTKLERGKKVAILH---LANR-LFVNETIGVNKRYNKLVNKHFRAEA 123
                   .|...|   |.:|.:.:     |.|   ||.| .|||.:..:.....::::.:..|..
Human   203 FTCVHQALKGFTT---KGVTSVSQ-----IFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANL 259

  Fly   124 EAIKLADRLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKP 188
            |            .||.||...|.:.:..::  ..|..|...|::||.:....|||.||...|:.
Human   260 E------------LINTWVAKNTNNKISRLL--DSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRM 310

  Fly   189 KVFYVSKSYQVNVNMMSQ----VGRFKMRTSTIDQII-----ELPFAYSNLSMVIVLPKD-NGSL 243
            :.|:...|. :.|.||:.    |..|      |||.:     :|..:: |||:||::|:: ...|
Human   311 EPFHFKNSV-IKVPMMNSKKYPVAHF------IDQTLKAKVGQLQLSH-NLSLVILVPQNLKHRL 367

  Fly   244 TQAEATIE-SYPQIVLTEMDVH------VQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISV-- 299
            ...|..:. |..:.::.::::.      :.||:.|:....:::..::.:   :.|:.|.|:::
Human   368 EDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKL---EFFDFSYDLNLCG 429

  Fly   300 LLNQSGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDDDNIY 364
            |......::|.:.|:..:|:.|.|..|.:|||..:      |.:::.|.|..||:|::.|..:.:
Human   430 LTEDPDLQVSAMQHQTVLELTETGVEAAAASAISV------ARTLLVFEVQQPFLFVLWDQQHKF 488

  Fly   365 --FRGRVVDP 372
              |.|||.||
Human   489 PVFMGRVYDP 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	92/385 (24%)
SERPING1	NP_000053.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..118
		7 X 4 AA tandem repeats of [QE]-P-T-[TQ]	85..119
		C1_inh	145..495	CDD:239005	92/388 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010