DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Serpine3

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	94/398 - (23%)
Similarity:	174/398 - (43%)	Gaps:	58/398 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 WILVTTSVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNL---- 66
            |:|.|     :|...||:|...:....|.:.||..|.:.:.::...|.|||..:|..||..
  Rat    29 WLLKT-----EFALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAEALGYTVQD 88

  Fly    67 PEDKKNVATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADR 131
            |..::.:.|:|    ..|....:...:.||..||:.....::..:.:.|:   |....:::|||.
  Rat    89 PRVREFLHTVY----ITLHNSSQGIGMELACTLFMQTGTSLSPCFVEQVS---RWANSSLELADF 146

  Fly   132 LKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAV------------MINAAFFKGYWKTRFDKM 184
            .:..        ..|::..|....||......|.:            :::...|:..|:.||..:
  Rat   147 SEPN--------TTTMEASKGTTRPSTGEGPGSPLWGRAGALSTQLSIVSTMTFQSSWQQRFSSV 203

  Fly   185 NTKPKVFYVSKSYQVNVNMMSQV-----GRFKMRTSTIDQIIELPFAYSNLSMVIVLPKDNGS-L 243
            ..:|..|..:....:.|..|.||     |:|:........::||.:.....|:::|||:|.|: |
  Rat   204 ALQPLPFTCAHGLVLQVPAMHQVAEVSYGQFQDAAGHKVDVLELLYLGRVASLLLVLPQDKGTPL 268

  Fly   244 TQAEATIES------YPQIVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNS-SSDISVLL 301
            ...|..:.:      ..::....|||.  ||:|:|..:.:|...|:|.||.|||:. .:::..:.
  Rat   269 DHIEPHLTARVIHLWTTRLKRARMDVF--LPRFRIQNQFDLKSILRSWGITDLFDPLKANLKGIS 331

  Fly   302 NQSGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDDDNIYFR 366
            .:.|..:|:|.|||.:|:.|||..:.:|:|..:...|    ....|..:.||:|::|:.:.:..|
  Rat   332 GRDGFYVSEVTHKAKMELSEEGTKSCAATAVLLLRRS----RTPAFKADRPFIFLLREHNTVAVR 392

  Fly   367 ---GRVVD 371
               |:|.:
  Rat   393 ITHGKVAN 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	90/384 (23%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	94/396 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110