Protein Alignment Spn28Da and SERPINE3

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 97/426 - (22%)
• Similarity: 169/426 - (39%)
• Gaps: 113/426 - (26%)

  Fly    16 QFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVATIYDKL 80
            :|...||:|......:.|.:.||..|.:.:.::..||:|:|..:|..||......|.|......:
Human    32 EFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAV 96

  Fly    81 LTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLDQ 145
            ...|....:...:.||..|||.....::..:.:.|:                        |..:.
Human    97 YATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVS------------------------WWANS 137

  Fly   146 TLDNVKDIIIPSDLT-PDESAV-------------------------MINAAF----------FK 174
            :|:       |:||: |:.:|:                         .::|||          |:
Human   138 SLE-------PADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQ 195

  Fly   175 GYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQV-----GRFKMRTSTIDQIIELPFAYSNLSMVI 234
            |.|:.||...:|:...|..:....:.|.||.|.     |:|:........::|||:..|.:|:.:
Human   196 GTWRKRFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFL 260

  Fly   235 VLPKDNGSLTQAEATIESYPQIVLTEMDVH------------VQLPKFKIDFRMELVETLKSMGI 287
            |||:|       :.|..|:.:..||...:|            |.||:|:|..:..|...|.|.|:
Human   261 VLPRD-------KDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGV 318

  Fly   288 QDLFNS-SSDISVLLNQSGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNS 351
            .|||:. .:::..:..|.|..:|:.:|||.||:.|||..|..|:|..:...|    .:..|..:.
Human   319 TDLFDPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRS----RIPIFKADR 379

  Fly   352 PFVFMIRDDD---NIYFRGRVVDPLKKSNPIDRITI 384
            ||::.:|:.:   .::|              |||.|
Human   380 PFIYFLREPNTGITVFF--------------DRIQI 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	93/409 (23%)
SERPINE3	NP_001094790.1	SERPIN	31..399	CDD:238101	94/422 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		4/30 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020