Protein Alignment Spn28Da and SERPINB4

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 115/387 - (29%)
• Similarity: 203/387 - (52%)
• Gaps: 36/387 - (9%)

  Fly    16 QFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPE------------ 68
            :|...|::.| :.:|:.||..||:.:...:.|:|:||..|||.::...|:..:
Human    10 KFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATY 73

  Fly    69 --DKK-NVATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLAD 130
              |:. ||...:.||||:..:......|.:||:||..:|....:.|...:.|.::...|:...|:
Human    74 HVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFAN 138

  Fly   131 -----RLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKV 190
                 |.|    ||.||..||.:.:|::.....:..|.:.|::||.:|||.|:.:|.|.|||.:.
Human   139 APEESRKK----INSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEK 199

  Fly   191 FYVSKSYQVNVNMMSQVG--RFKMRTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESY 253
            |:.:|:...:|.||.|..  .|.:......:::|:|:...:|||:::||.:...|.:.|..:.:.
Human   200 FWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAE 264

  Fly   254 PQIVLTEMD------VHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVV 312
            ..:..|.:.      |.:.||:||::...:|.:||::||:.::||..:|:|.:....|..:|:|:
Human   265 KLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVL 329

  Fly   313 HKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDD--DNIYFRGRVVDP 372
            ||||:|:.|||..|.:|:|..:..||..:|: ..|..|.||:|.||.:  ::|.|.||...|
Human   330 HKAFVEVTEEGVEAAAATAVVVVELSSPSTN-EEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	113/382 (30%)
SERPINB4	NP_002965.1	SERPIN	4..390	CDD:320777	114/385 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76659
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.880