Protein Alignment Spn28Da and SERPINI2

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001012303.2
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 103/369 - (27%)
• Similarity: 184/369 - (49%)
• Gaps: 16/369 - (4%)

  Fly    16 QFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVA-TIYDK 79
            :|...||:.....:|. |||.|||.:.:.:.|:.:||.|....::|..|...|...... .:...
Human    28 EFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKS 91

  Fly    80 LLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLD 144
            ..:.:...|:....:|||.|::.|...|.::|.....:.|::..:.:...|....|..|:.||..
Human    92 FFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVER 156

  Fly   145 QTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGR 209
            :|...:||:....:..|....|::||.:|||.||.:|.|.:|:...|.......|.:.||..:.|
Human   157 KTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKALLR 221

  Fly   210 FK----MRTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQIV--LTEM---DVHV 265
            .|    ..:|...|::||.:.....|::|:||.:...:.:.|..|.: .||:  |:||   :|.:
Human   222 TKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEEVEKLITA-QQILKWLSEMQEEEVEI 285

  Fly   266 QLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHKAFIEIDEEGGSAGSAS 330
            .||:||::.:::..:.|.|:.|.::|:...|:|.:.:.|...:|||..|.|.||:|:|..|.:::
Human   286 SLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATST 350

  Fly   331 ASPIRGLSDYATSVVTFTVNSPFVFMIRDD--DNIYFRGRVVDP 372
            ...|..:...|.|  .|..|.||:|:::.:  ::|.|.|||.:|
Human   351 GIHIPVIMSLAQS--QFIANHPFLFIMKHNPTESILFMGRVTNP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	100/364 (27%)
SERPINI2	NP_001012303.2	serpinI2_pancpin	23..392	CDD:381042	102/367 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.930