Protein Alignment Spn28Da and SERPINB8

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001353127.1
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 112/371 - (30%)
• Similarity: 191/371 - (51%)
• Gaps: 18/371 - (4%)

  Fly    15 GQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVATIYDK 79
            |.|...|::...:::...|:..||:.:...::|:.|||.|:||.::..||.|.:| .::...:..
Human     9 GTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD-GDIHRGFQS 72

  Fly    80 LLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLA-DRLKAAWAINDWVL 143
            ||:::.|.....:|..|||||..:|......:.:...|.::||.|.:..| |..:....|||||.
Human    73 LLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVA 137

  Fly   144 DQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVG 208
            ::|...:.:::....:.|....|::||.:|||.|..:||:..|:..:|..::. :..|.||.:..
Human   138 EKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEE-KKTVQMMFKEA 201

  Fly   209 RFKM--RTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQI-------VLTEMDVH 264
            :|||  ......|::|||:....|||||:||.||..|...|..: :|.:.       .||:..|.
Human   202 KFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL-TYEKFKAWTNSEKLTKSKVQ 265

  Fly   265 VQLPKFKIDFRMELVETLKSMGIQDLFN-SSSDISVLLNQSGTRISQVVHKAFIEIDEEGGSAGS 328
            |.||:.|::...:|...|:.:|:.|.|: :.:|.|.:..:....:|:|.||.|:|::|||..|.:
Human   266 VFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAA 330

  Fly   329 ASASPIRGLSDYATSVVTFTVNSPFVFMIRDDDN--IYFRGRVVDP 372
            |:| .:|. |..:.....|..:.||:|.||....  |.|.||...|
Human   331 ATA-VVRN-SRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	109/365 (30%)
SERPINB8	NP_001353127.1	SERPIN	4..374	CDD:320777	111/369 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.930