Protein Alignment Spn28Da and SERPINB6

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 116/393 - (29%)
• Similarity: 204/393 - (51%)
• Gaps: 29/393 - (7%)

  Fly     4 LCWIL---------VTTSVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANE 59
            :||.|         |.....|.|...|.::..:||.: |:..||:.:...::|:.|||.||||.:
Human    67 ICWGLLHIKSAIMDVLAEANGTFALNLLKTLGKDNSK-NVFFSPMSMSCALAMVYMGAKGNTAAQ 130

  Fly    60 LRTAL--NLPEDKKNVATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAE 122
            :...|  |......::...:..|||::.:.....:|.:|||||..::......:.....|.::||
Human   131 MAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAE 195

  Fly   123 AEAIKLADRL-KAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNT 186
            .|.:.....: |:...||.||.::|...:.:::.|..:.|....|::||.:|:|.|..:|||.||
Human   196 MEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENT 260

  Fly   187 KPKVFYVSKSYQVNVNMMSQVGRFKMRT---STIDQIIELPFAYSNLSMVIVLPKDNGSL--TQA 246
            :.::|.|||:.:..|.||.:...|| :|   ....||:.||:....|:|:|:||.:...|  .:.
Human   261 EERLFKVSKNEEKPVQMMFKQSTFK-KTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEK 324

  Fly   247 EATIESYPQ----IVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFN-SSSDISVLLNQSGT 306
            |.|.|.:.:    .::.|.:|.|.||:||::...::...|:::|:.|.|. ..:|.|. ::|:..
Human   325 ELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSG-MSQTDL 388

  Fly   307 RISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDD--DNIYFRGRV 369
            .:|:||||:|:|::|||..|.:|:|:.:  :...|..|..|..:.||:|.|:..  :.|.|.||.
Human   389 SLSKVVHKSFVEVNEEGTEAAAATAAIM--MMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRF 451

  Fly   370 VDP 372
            ..|
Human   452 SSP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	109/367 (30%)
SERPINB6	XP_011512974.1	PAI-2	82..454	CDD:239013	111/376 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.830