Protein Alignment Spn28Da and SERPINA10

DIOPT Version :10

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 99/393 - (25%)
• Similarity: 189/393 - (48%)
• Gaps: 44/393 - (11%)

  Fly     6 WILVTTSVLGQFTKQLYRSFLQD---NKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNL- 66
            |::.:...|.:.|.....|.|:.   ....|::.||..:.:.|:.:::||.|.|..:::..|:|
Human   107 WLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 171

  Fly    67 ---PEDKKNVATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKL 128
               |.....:.:::..|...|.|..::.:.. .:..|:::...|.:.:..|..::|..|...:..
Human   172 ALKPTKPGLLPSLFKGLRETLSRNLELGLTQ-GSFAFIHKDFDVKETFFNLSKRYFDTECVPMNF 235

  Fly   129 ADRLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYV 193
            .:..:|...:|.::..:|...:..:.  .::.|:...::::...|||.|.|.||.:.|:...|::
Human   236 RNASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHL 298

  Fly   194 SKSYQVNVNMMSQVGRFKMRTSTIDQ-----IIELPFAYSNLSMVIVLPKDNGSLTQAEATIESY 253
            .|...:.|.||...|:|   .||.|:     :::||: ..|.:|::||.:..|.    ...:|.|
Human   299 DKYKTIKVPMMYGAGKF---ASTFDKNFRCHVLKLPY-QGNATMLVVLMEKMGD----HLALEDY 355

  Fly   254 PQIVLTE--------MDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGT---- 306
            ....|.|        .::.|..||||:|.:.|:.|.|:.|||:.:|:..:|:|.|   |.|
Human   356 LTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSEL---SATGRNL 417

  Fly   307 RISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDDDN--IYFRGRV 369
            ::|:|:.:..||:||.|..|.:...|.|   :.|:...| ..|:.||.|||.::.:  :.|.|||
Human   418 QVSRVLQRTVIEVDERGTEAVAGILSEI---TAYSMPPV-IKVDRPFHFMIYEETSGMLLFLGRV 478

  Fly   370 VDP 372
            |:|
Human   479 VNP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	serpin42Dd-like_insects	12..372	CDD:381070	97/385 (25%)
SERPINA10	XP_016876842.1	serpinA10_PZI	107..482	CDD:381011	99/393 (25%)