Protein Alignment Spn28Da and SERPINA5

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 101/384 - (26%)
• Similarity: 185/384 - (48%)
• Gaps: 37/384 - (9%)

  Fly     9 VTTSVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNL---PEDK 70
            |..|....||..|||:........:|..||:.:.:.::|:.:||..:|..::...|.|   ...:
Human    40 VAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSE 104

  Fly    71 KNVATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAA 135
            |.:...:.:||.:|.:.:....|.|.|.||.:..:.:...:...:...:.|:.......|...|.
Human   105 KELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAM 169

  Fly   136 WAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVN 200
            ..|||:|..||...:.|::  .:|..:...:|:|..|||..|:|.|:...|:.:.|||:....|.
Human   170 KQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVR 232

  Fly   201 VNMMSQVGRFK--MRTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQ-----AEATIESYPQIVL 258
            |.|||:..::.  :..:...:::.:|: ..|.:.:.:||.: |.:.|     :|.|:..:.: :.
Human   233 VPMMSREDQYHYLLDRNLSCRVVGVPY-QGNATALFILPSE-GKMQQVENGLSEKTLRKWLK-MF 294

  Fly   259 TEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHKAFIEIDEEG 323
            .:..:.:.||||.|:...:|.:.|.|:||.::|.|.:|:|.:.|.|..::|::||||.:|:||.|
Human   295 KKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESG 359

  Fly   324 GSAGSASASPIRGLSDYATSVVTF----------TVNSPFVFMIRDDDNIYFRGRVVDP 372
            ..|.:|:.           ::.||          ..|.||:..| .|:||.|.|:|..|
Human   360 TRAAAATG-----------TIFTFRSARLNSQRLVFNRPFLMFI-VDNNILFLGKVNRP 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	97/372 (26%)
SERPINA5	NP_000615.3	alpha-1-antitrypsin_like	44..403	CDD:239011	97/375 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010