DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Serpinb6b

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_038951899.1	Gene:	Serpinb6b / 364705	RGDID:	1310452	Length:	388	Species:	Rattus norvegicus

Alignment Length:	391	Identity:	116/391 - (29%)
Similarity:	201/391 - (51%)	Gaps:	44/391 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDK------KNV 73
            |.|...|.::..:|:.: |::.|||.:..|::|:.|||.|.||:::..||:|  ||      ::|
  Rat     9 GTFAFNLLKTLGEDSSK-NVLFSPLSISSGLAMVFMGAKGTTAHQMIQALSL--DKCSGRGSRDV 70

  Fly    74 ATIYDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAI--KLADRLKAAW 136
            ...:..||.|:.:.....:|..|||||..:|..:...:.....|.:.||.|.:  |.|.. ::..
  Rat    71 HQGFQSLLAKVNKTGTQYLLKTANRLFGEKTFDILASFKDACRKFYEAEMEELDFKGAPE-QSRQ 134

  Fly   137 AINDWVLDQT-----------LDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKV 190
            .||.||..:|           ...:.:::....:..:...|::||.:|||.||.:|:|.:|:...
  Rat   135 HINTWVAKKTEGQSISLNWNSQKKITELLSSGSVNANTPLVLVNAIYFKGNWKKQFNKEDTQEMP 199

  Fly   191 FYVSKSYQVNVNMMSQVGRFKM----RTSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIE 251
            |.|:|:.:..|.||.:...|||    ..||  .|:.||:..:.|:|:|:||.::..|...|..|
  Rat   200 FKVTKNEEKPVKMMFKKSTFKMTYVEEIST--TILLLPYVGNELNMIIMLPDEHIELRMVEKEI- 261

  Fly   252 SYPQIV-------LTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSS-SDISVLLNQSGTRI 308
            :|.:.:       :.|.:|.|.|||||::...::.:.|..:|:.|.|... :|.|.:.::.|..:
  Rat   262 TYKKFIEWTSLDKMEEREVEVFLPKFKLEENHDMKDVLHRLGMTDAFEQGMADFSGIASKEGLFL 326

  Fly   309 SQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDD--DNIYFRGRVVD 371
            |:|:||:|:|::|||..|.:|:|:.:    .:...|..|..|.||:|.|:..  :.|.|.||...
  Rat   327 SKVIHKSFVEVNEEGTEAAAATAANV----TFRCMVPYFCANHPFLFFIQHSRTNGIVFCGRFSS 387

  Fly   372 P 372
            |
  Rat   388 P 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	113/385 (29%)
Serpinb6b	XP_038951899.1	serpin	1..388	CDD:422956	115/389 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830