DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Spn47C

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	113/372 - (30%)
Similarity:	190/372 - (51%)	Gaps:	23/372 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 FTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNL-PEDKKNVATIYDKL 80
            |.:.|:|:...:....|::.||......|:::.|||.|.:|:|||:.|.| ..:|..||..:.:.
  Fly    18 FARNLFRALNDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVSNKSEVAKQHAES 82

  Fly    81 LT-KLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLD 144
            .| :....||...|.|..||:|||...:...:|.:..:.|.|||.::...:...:...:|.|:..
  Fly    83 WTDECSCAKKGVALRLVTRLYVNEEEKIRTDFNDMALEFFNAEAYSLNYLNPEDSVKKVNKWLEK 147

  Fly   145 QTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGR 209
            .|...|:::..|.....|.|.:::|:.||:..|...|.:..|:...|:::...::.|:||.|:|:
  Fly   148 HTFYTVRNLFTPEVFNSDSSVILVNSLFFRAKWNKIFPQQLTQIDDFWINPRQRMEVSMMRQIGQ 212

  Fly   210 FKMRTS--TIDQIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQIVLTEM-------DVHV 265
            |:...|  ...||::|||..|||:|:|:||.....|.:.|   |...|:.:.|:       :|.|
  Fly   213 FRYGESKKLKSQILQLPFERSNLTMMIILPTAIDGLPELE---EKLGQLDMNEVAAKSLMKEVDV 274

  Fly   266 QLPKFKIDFRMELVETLKSMGIQDLFNS-SSDISVLLN-QSGTRISQVVHKAFIEIDEEGGS-AG 327
            .:|||:|:..::|...|:.|||..:|:: .:|:|.|.. ::..:||:..||.|:.:.|.|.. |.
  Fly   275 TIPKFRIECTVDLKVPLQKMGINSVFDAGQADLSDLFEMKTPQKISEARHKVFLNVTEFGCEVAP 339

  Fly   328 SASASP--IRGLSDYATSVVTFTVNSPFVFMIRDDDNIYFRGRVVDP 372
            .|...|  ::...|..    .|..:.||||.|||..|:||.|..|.|
  Fly   340 EAEVQPEVLKKNPDRK----FFKADRPFVFAIRDRKNVYFVGHFVKP 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	111/367 (30%)
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	111/367 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446402
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140751at6656
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	6	5.950