DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Serpina7

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_808588.3	Gene:	Serpina7 / 331535	MGIID:	3041197	Length:	426	Species:	Mus musculus

Alignment Length:	386	Identity:	98/386 - (25%)
Similarity:	164/386 - (42%)	Gaps:	36/386 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVATI 76
            |:...|...|||....:|...||..||:.:.:.::|:..|:..:|..::...|..        .:
Mouse    55 SINADFAFSLYRRLSVENPDLNIFFSPVSISVALAMLSFGSGSSTQTQILEVLGF--------NL 111

  Fly    77 YDKLLTKLERG-----------KKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLAD 130
            .|..:|:|::|           |....|.:.|.:|:.:.:....::...|...:..|..:...::
Mouse   112 TDTPVTELQQGFQHLICSLNFPKNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSN 176

  Fly   131 RLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKV-FYVS 194
            ...|...||.:|..||...:..:|  ..|..:...:::|...|:..|...|....|:... |.|.
Mouse   177 VSAAQHKINSYVEKQTKGKIVGLI--QGLKLNIIMILVNYIHFRAQWANPFRVSKTEESSNFSVD 239

  Fly   195 KSYQVNVNMMSQVGRFKMRTSTIDQIIELPFAYS-NLSMVIVLPKDNGSLTQAEATIESYP---- 254
            ||..|.|.||.|:.::............|...|| |...:.||||: |.:...||.:.|..
Mouse   240 KSTTVQVPMMHQLEQYYHYVDMELNCTVLQMDYSENALALFVLPKE-GHMEWVEAAMSSKTLKKW 303

  Fly   255 QIVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHKAFIEI 319
            ..:|.:..|.:.:|||.|....:|..||:.||::|.|..|:|...:...||.::|...|||.:.|
Mouse   304 NYLLQKGWVELFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITEDSGLKLSYAFHKAVLHI 368

  Fly   320 DEEGGSAGSASASPIRGLSDYATSVVTFTV---NSPFVFMI--RDDDNIYFRGRVVDPLKK 375
            .|||...|   |||..|..|.........|   :..|:.||  :...::.|.|::|:|.|:
Mouse   369 GEEGTKEG---ASPEVGSLDQQEVPPLHPVIRLDRAFLLMILEKRTRSVLFLGKLVNPTKQ 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	94/374 (25%)
Serpina7	NP_808588.3	alpha-1-antitrypsin_like	57..419	CDD:239011	93/375 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100