DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Serpinb13

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001100638.1	Gene:	Serpinb13 / 304690	RGDID:	1304661	Length:	389	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	116/393 - (29%)
Similarity:	187/393 - (47%)	Gaps:	41/393 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 TTSVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTAL---------N 65
            ||..|....|:|.::     ...|:..|||.:...:.|||:|..|.||:||:..|         .
  Rat     8 TTHFLFDLFKELNKT-----SDGNVFFSPLGISTAIGMILLGTQGATASELQKVLYSEQGTGSSR 67

  Fly    66 LPEDKKNVATI------YDKLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAE 124
            |..::|.:...      :.||||::.:..|...|.::|||:...|....::|...|.|::.|..|
  Rat    68 LKSEEKEIEKTEEIHHQFQKLLTEISKPTKDYDLIISNRLYGERTYLFLQKYIDYVEKYYHASLE 132

  Fly   125 AIKLADRLKAA----WAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMN 185
            .:   |.:.||    ..||.||..||.:.|||:.....|......|:||..:|||.|...|.|.:
  Rat   133 PV---DFVNAADESRKKINSWVESQTNEKVKDLFPEGSLNSSTKLVLINTVYFKGLWDREFKKEH 194

  Fly   186 TKPKVFYVSKSYQVNVNMMSQVGRFKMRTSTID---QIIELPFAYSNLSMVIVLPKDNGSLTQ-- 245
            ||.:.|:::|:....|.||:|...|.. |...|   :|:.:|:..|:.||.::||.|...|.:
  Rat   195 TKEEDFWLNKNISKPVQMMAQCSSFSF-TLLEDLQAKIVGIPYKNSDFSMFVLLPNDIDGLEKII 258

  Fly   246 ----AEATIESYPQIVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGT 306
                .|..:|......|.:..|.::||:.|::...:|..||:::||...|:..:|.|.:...||.
  Rat   259 DKLSPEKLVEWTSPGQLKQRKVDLRLPRLKVEETYDLQPTLEAVGIHSAFSEHADYSGMSAHSGL 323

  Fly   307 RISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMI--RDDDNIYFRGRV 369
            :....:|::|:.:.|||..|.:.:....:.||  |.|......|.||:|.:  |:.|:|.|.||.
  Rat   324 QTQNFLHRSFLVVTEEGVEATAGTGVGFKVLS--AASCELVHCNHPFLFFVRHRESDSILFFGRF 386

  Fly   370 VDP 372
            ..|
  Rat   387 SSP 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	111/382 (29%)
Serpinb13	NP_001100638.1	SERPIN	4..389	CDD:294093	115/391 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930