DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and serpinh1b

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001296752.1	Gene:	serpinh1b / 30449	ZFINID:	ZDB-GENE-990415-93	Length:	405	Species:	Danio rerio

Alignment Length:	398	Identity:	99/398 - (24%)
Similarity:	191/398 - (47%)	Gaps:	39/398 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LCWILVTTSVLGQFTK-----------------QLYRSFLQDNKQYNIIASPLCVEIGMSMILMG 51
            ||  |:..:|.|:..|                 .||.:..::....||:.||:.|...:.|:.||
Zfish     9 LC--LLAVAVSGEDKKLSTHATSMADTSANLAFNLYHNVAKEKGLENILISPVVVASSLGMVAMG 71

  Fly    52 ADGNTANELRTALNLPEDK-KNVATIYDKLLTKL-ERGKKVAILHLANRLFVNETIGVNKRYNKL 114
            :..:||:::::.|.....| :::.|...:|||:: :...:.....::|||:...::...:.:.|.
Zfish    72 SKSSTASQVKSVLKADALKDEHLHTGLSELLTEVSDPQTRNVTWKISNRLYGPSSVSFAEDFVKN 136

  Fly   115 VNKHFRAEAEAIKLADRLKAAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKT 179
            ..||:..|...|...|:..|..:||:|....|...:.:  |..|:...:.|:::||.|||.:|..
Zfish   137 SKKHYNYEHSKINFRDKRSAINSINEWAAKTTDGKLPE--ITKDVKNTDGAMIVNAMFFKPHWDE 199

  Fly   180 RFDKMNTKPKVFYVSKSYQVNVNMMSQVGRFKMRTSTIDQ--IIELPFAYSNLSMVIVLPKDNGS 242
            :|.......:.|.|::|:.|:|.||.:.|.:.....|.::  |:.:|.|:...||:.::|.....
Zfish   200 KFHHKMVDNRGFLVTRSHTVSVPMMHRTGIYGFYEDTENRFLIVSMPLAHKKSSMIFIMPYHVEP 264

  Fly   243 LTQAEATIESYPQI-----VLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFN-SSSDISVLL 301
            |.:.| .:.:..|:     .|.|..|.:.|||..::...:|.:.|..:|:.:..: |.:|:|.:.
Zfish   265 LDRLE-NLLTRQQLDTWISKLEERAVAISLPKVSMEVSHDLQKHLGELGLTEAVDKSKADLSNIS 328

  Fly   302 NQSGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDD--DNIY 364
            .:....:|.|.|.:.:|.|.||.....:    |.| |:...:...|..:.||:|:::|:  ::|.
Zfish   329 GKKDLYLSNVFHASSLEWDTEGNPFDPS----IFG-SEKMRNPKLFYADHPFIFLVKDNKTNSIL 388

  Fly   365 FRGRVVDP 372
            |.||:|.|
Zfish   389 FIGRLVRP 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	91/381 (24%)
serpinh1b	NP_001296752.1	hsp47	28..393	CDD:239001	90/372 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920