DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Serpinb8

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001099418.1	Gene:	Serpinb8 / 288937	RGDID:	1309833	Length:	375	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	110/373 - (29%)
Similarity:	190/373 - (50%)	Gaps:	21/373 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVATIYDK 79
            |.|...|.:...:::|..|:...|:.|...::|:.:||.||||.::...|.|..| .:|...:..
  Rat     9 GSFAISLLKILGEEDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSQVLGLSGD-GDVHQGFQT 72

  Fly    80 LLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIK-LADRLKAAWAINDWVL 143
            ||.::.:.....:|..|.|||..|:......:.:...|.::|..|.:. :.|.......||||||
  Rat    73 LLAEVNKSGTQYLLKSACRLFGEESCDFLSTFKESCQKFYQAGIEEMSFVKDTEGCRKRINDWVL 137

  Fly   144 DQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVG 208
            ::|...:.:::.|..:.|....|::||.:|||.||.:||:..|:...|..::..:..|.||.:..
  Rat   138 EKTEGKISEVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFKTNQEEKKTVQMMFKHA 202

  Fly   209 RFKMRTSTID----QIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQI-------VLTEMD 262
            :|||  :.:|    |::.||:|...||||::||.::..||..|..: :|.::       .|||..
  Rat   203 KFKM--AHVDEVNAQVLALPYAEDELSMVVLLPDESSDLTVVEKAL-TYEKLRAWTNPETLTESK 264

  Fly   263 VHVQLPKFKIDFRMELVETLKSMGIQDLF-NSSSDISVLLNQSGTRISQVVHKAFIEIDEEGGSA 326
            |.|..|:.|::...:|...|:|:|:.|.| .:.:|.|.:.::....:|:|.||.|:|::|||..|
  Rat   265 VQVFFPRLKLEESYDLETVLQSLGMTDAFEETKADFSGMTSKKNVPVSKVAHKCFVEVNEEGTEA 329

  Fly   327 GSASASPIRGLSDYATSVVTFTVNSPFVFMI--RDDDNIYFRGRVVDP 372
             :|:.:.||........ ..|..:.||:|.|  :...:|.|.||...|
  Rat   330 -AATTAVIRNTRSCRIE-PRFCADRPFLFFIWHQKTSSILFCGRFSSP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	107/367 (29%)
Serpinb8	NP_001099418.1	SERPIN	4..375	CDD:294093	109/371 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.930