DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn28Da and Serpinb8

DIOPT Version :9

Sequence 1:NP_001036345.1 Gene:Spn28Da / 34082 FlyBaseID:FBgn0051902 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_035589.1 Gene:Serpinb8 / 20725 MGIID:894657 Length:374 Species:Mus musculus


Alignment Length:373 Identity:111/373 - (29%)
Similarity:186/373 - (49%) Gaps:22/373 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 GQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVATIYDK 79
            |.|...|.:...:.:|..|:...|:.|...::|:.:||.||||.::...|.| ....:|...:..
Mouse     9 GSFAISLLKILSEKDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSEVLGL-SGNGDVHQSFQT 72

  Fly    80 LLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLA-DRLKAAWAINDWVL 143
            ||.::.:.....:|..|.|||..|:......:.:..:|.::|..|.:..| |.......|||||.
Mouse    73 LLAEINKTDTQYLLKSACRLFGEESCDFLSTFKESCHKFYQAGLEELSFAKDTEGCRKHINDWVS 137

  Fly   144 DQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVG 208
            ::|...:.:::.|..:.|....|::||.:|||.||.:||:..|:...|..::. :..|.||.:..
Mouse   138 EKTEGKISEVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFKTNQE-KKTVQMMFKHA 201

  Fly   209 RFKMRTSTID----QIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQI-------VLTEMD 262
            :|||  ..:|    |::.||:|...|||||:||.::..|...|..: :|.::       .|||..
Mouse   202 KFKM--GHVDEVNMQVLALPYAEEELSMVILLPDESTDLAVVEKAL-TYEKLRAWTNPETLTESQ 263

  Fly   263 VHVQLPKFKIDFRMELVETLKSMGIQDLFNSS-SDISVLLNQSGTRISQVVHKAFIEIDEEGGSA 326
            |.|.||:.|::...:|...|:::|:.|.|..: :|.|.:..:....:|:|.||.|:|::|||..|
Mouse   264 VQVFLPRLKLEESYDLETVLQNLGMTDAFEETRADFSGMTTKKNVPVSKVAHKCFVEVNEEGTEA 328

  Fly   327 GSASASPIRGLSDYATSVVTFTVNSPFVFMI--RDDDNIYFRGRVVDP 372
            .:|:| .||......|. ..|..:.||:|.|  ....:|.|.||...|
Mouse   329 AAATA-VIRNARCCRTE-PRFCADHPFLFFIWHHKTSSILFCGRFSSP 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn28DaNP_001036345.1 SERPIN 16..369 CDD:238101 108/367 (29%)
Serpinb8NP_035589.1 SERPIN 4..374 CDD:294093 110/371 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X28
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
65.930

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